The Administrative Core will provide four major services: Professional Direction for the aggregate PPG, Communication and Coordination of PPG-related activities, Organization of Program Project Meetings and Biostatistical Support for Component Project Investigators and Core Leaders. The Administrative Core will therefore provide strong centralized scientific and administrative leadership to facilitate synergistic interactions between the three Projects and three Cores of this Program Project. Dr. Richard Peek, Principal Investigator, has primary responsibility for all aspects of the Program and the Administrative Core. He will be aided by the Project Leaders, Core Directors, members of the Scientific Advisory Boards, and administrative personnel. The administrative staff of the Core will oversee all annual budgets, monitor expenses, and provide monthly statements of financial activities. Biostatistical analysis and interpretation will be provided to all Program Project participants by Dr. Tatsuki Koyama, the Administrative Core's Biostatistician. In addition, all Program-related meetings will be scheduled through this Core. These include monthly meetings of Project and Core leaders to evaluate productivity, allocate core usage and Program resources, and discuss future directions. A bi-monthly scientific meeting will also allow investigators to present current data, identify problems, and discuss solutions. Arrangements for the Scientific Advisory Board meetings, planned for every other year of the Project period, as well as generation of materials to be reviewed will be handled through the Administrative Core. The Administrative Core will organize and coordinate 1 retreat every other year for Program Project participants and the Internal and External advisors. Finally, this Core will prepare, generate, and assemble materials required for the annual progress reports and will ensure that all additional NIH and institutional reporting requirements concerning the Program Project's activities are completed in a timely manner.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1-RPRB-C (O1))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Vanderbilt University Medical Center
United States
Zip Code
Sierra, Johanna C; Asim, Mohammad; Verriere, Thomas G et al. (2017) Epidermal growth factor receptor inhibition downregulates Helicobacter pylori-induced epithelial inflammatory responses, DNA damage and gastric carcinogenesis. Gut :
Hardbower, Dana M; Asim, Mohammad; Luis, Paula B et al. (2017) Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications. Proc Natl Acad Sci U S A 114:E751-E760
Gobert, Alain P; Wilson, Keith T (2017) Effect of CO2 on Peroxynitrite-Mediated Bacteria Killing: Response to Tsikas et al. Trends Microbiol 25:602-603
Kyburz, A; Urban, S; Altobelli, A et al. (2017) Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy. Clin Exp Allergy 47:1331-1341
Varga, Matthew Gordon; Peek, Richard M (2017) DNA Transfer and Toll-like Receptor Modulation by Helicobacter pylori. Curr Top Microbiol Immunol 400:169-193
Feichtinger, René G; Neureiter, Daniel; Skaria, Tom et al. (2017) Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis. Oxid Med Cell Longev 2017:1320241
Loh, John T; Beckett, Amber C; Scholz, Matthew B et al. (2017) High salt conditions alter transcription of Helicobacter pylori genes encoding outer membrane proteins. Infect Immun :
Kim, Aeryun; Servetas, Stephanie L; Kang, Jieun et al. (2017) Correction: Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical Isolates. PLoS One 12:e0176468
Xiong, Menghua; Bao, Yan; Xu, Xin et al. (2017) Selective killing of Helicobacter pylori with pH-responsive helix-coil conformation transitionable antimicrobial polypeptides. Proc Natl Acad Sci U S A 114:12675-12680
Zhu, Shoumin; Soutto, Mohammed; Chen, Zheng et al. (2017) Helicobacter pylori-induced cell death is counteracted by NF-?B-mediated transcription of DARPP-32. Gut 66:761-762

Showing the most recent 10 out of 189 publications