The goal of the Administrative Core is to provide leadership, scientific exchange and administrative support to scientists and staff of this program project. The organizational activities include weekly laboratory data meetings, monthly laboratory data meetings and journal clubs, monthly laboratory seminars, monthly program projects leaders'meetings and annual reviews with the external advisory board members. The administrative core disseminates information to investigators regarding lectures of visiting scientists and educational activities in the Department and in the Lombard/ Comprehesive Cancer Center (LCCC). The Administrative Core also supports a Biostatistical Program which assists members in clinical and basic research study design, data analysis, and database management. Administrative oversight includes assurance of compliance with regulatory agencies, as it pertains to the institutional review board, the clinical research committee of the LCCC as well as the various environmental and safety related agencies. The administrative core component maintains the appropriate records and prepares the necessary reports. With input from the external advisory board and the committee of project leaders, the PI makes decisions regarding research directions and appropriateness of research allocations. In summary, the administrative core allows for the smooth operation of the research program.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1-RPRB-O (M1))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas MD Anderson Cancer Center
United States
Zip Code
Zhi, Xiuling; Lin, Ling; Yang, Shaoxian et al. (2015) ?II-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin. Hepatology 61:598-612
Javle, Milind; Smyth, Elizabeth C; Chau, Ian (2014) Ramucirumab: successfully targeting angiogenesis in gastric cancer. Clin Cancer Res 20:5875-81
Kiriyama, Shigehisa; Yokoyama, Shozo; Ueno, Masaki et al. (2014) CEACAM1 long cytoplasmic domain isoform is associated with invasion and recurrence of hepatocellular carcinoma. Ann Surg Oncol 21 Suppl 4:S505-14
Xiao, Junfeng; Zhao, Yi; Varghese, Rency S et al. (2014) Evaluation of metabolite biomarkers for hepatocellular carcinoma through stratified analysis by gender, race, and alcoholic cirrhosis. Cancer Epidemiol Biomarkers Prev 23:64-72
Bailey, Ann M; Zhan, Le; Maru, Dipen et al. (2014) FXR silencing in human colon cancer by DNA methylation and KRAS signaling. Am J Physiol Gastrointest Liver Physiol 306:G48-58
Lim, Jeong A; Baek, Hye Jung; Jang, Moon Sun et al. (2014) Loss of *2-spectrin prevents cardiomyocyte differentiation and heart development. Cardiovasc Res 101:39-47
Mitra, Abhisek; Satelli, Arun; Yan, Jun et al. (2014) IL-30 (IL27p28) attenuates liver fibrosis through inducing NKG2D-rae1 interaction between NKT and activated hepatic stellate cells in mice. Hepatology 60:2027-39
Dibra, Denada; Mishra, Lopa; Li, Shulin (2014) Molecular mechanisms of oncogene-induced inflammation and inflammation-sustained oncogene activation in gastrointestinal tumors: an under-appreciated symbiotic relationship. Biochim Biophys Acta 1846:152-60
Huang, Chen; Du, Jiawei; Xie, Keping (2014) FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesis. Biochim Biophys Acta 1845:104-16
Muñoz, Nina M; Katz, Lior H; Shina, Ji-Hyun et al. (2014) Generation of a mouse model of T-cell lymphoma based on chronic LPS challenge and TGF-? signaling disruption. Genes Cancer 5:348-52

Showing the most recent 10 out of 41 publications