This program project (P01) explores the question of whether different tobacco control policies (e.g., product labeling, smoke-free policies, price and taxation, and product regulation) are relatively consistent or inconsistent in effectiveness across different countries with varying incomes and cultures. The proposed research builds upon the work started by the International Tobacco Control Policy Evaluation consortium (referred to as the ITC Project), which has been supported in part by our Transdisciplinary Tobacco Use Research Center grant (TTURC - P50 CA111236). The ITC Project was established with the aim of applying rigorous evaluation methods to try to understand the impact of the tobacco control policies implemented as part of the Framework Convention on Tobacco Control (FCTC). The strength of the ITC Project has been its unique design utilizing multiple country comparisons, longitudinal cohorts of smokers tracked annually, and a pre-specified, theory-driven mediational model to test hypotheses about the anticipated effects of a given tobacco control policy. Each of the three projects in this application incorporate measures and methods to assess the impact of agent, host, and environmental factors on tobacco use behaviors with slight variations in approach and emphasis. Project 1 examines the relative consistency of different tobacco control policies measured at the population level across a diverse group of 18 high and low and middle-income countries (LMICs). Project 2 extends the work of Project 1 within the area of tobacco packaging and labeling with a focus upon building the evidence for novel policies in LMICs. Project 3 explores how tobacco products differ between high and LMICs, how policies impact product features, and how innate host characteristics such as nicotine metabolism interact with product features to influence tobacco use behaviors. Collectively, the findings from this P01 will help define how different tobacco control policies work, the generality of effects between and within countries, and ultimately inform governments about the need to tailor policy interventions to achieve maximum effectiveness during the next critical five year period of FCTC policy implementation.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
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Special Emphasis Panel (ZCA1-RPRB-7 (J1))
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Vollinger, Robert
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Medical University of South Carolina
Schools of Medicine
United States
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Nargis, Nigar; Ruthbah, Ummul H; Hussain, A K M Ghulam et al. (2014) The price sensitivity of cigarette consumption in Bangladesh: evidence from the International Tobacco Control (ITC) Bangladesh Wave 1 (2009) and Wave 2 (2010) Surveys. Tob Control 23 Suppl 1:i39-47
Nargis, Nigar; Fong, Geoffrey T; Chaloupka, Frank J et al. (2014) The choice of discount brand cigarettes: a comparative analysis of International Tobacco Control surveys in Canada and the USA (2002-2005). Tob Control 23 Suppl 1:i86-96
Cummings, K Michael; Proctor, Robert N (2014) The changing public image of smoking in the United States: 1964-2014. Cancer Epidemiol Biomarkers Prev 23:32-6
Huang, Jidong; Chaloupka, Frank J; Fong, Geoffrey T (2014) Cigarette graphic warning labels and smoking prevalence in Canada: a critical examination and reformulation of the FDA regulatory impact analysis. Tob Control 23 Suppl 1:i7-12
Shang, Ce; Chaloupka, Frank J; Zahra, Nahleen et al. (2014) The distribution of cigarette prices under different tax structures: findings from the International Tobacco Control Policy Evaluation (ITC) Project. Tob Control 23 Suppl 1:i23-9
Tauras, John A; Chaloupka, Frank J; Quah, Anne Chiew Kin et al. (2014) The economics of tobacco control: evidence from the International Tobacco Control (ITC) Policy Evaluation Project. Tob Control 23 Suppl 1:i1-3
Fix, Brian V; Hyland, Andrew; O'Connor, Richard J et al. (2014) A novel approach to estimating the prevalence of untaxed cigarettes in the USA: findings from the 2009 and 2010 international tobacco control surveys. Tob Control 23 Suppl 1:i61-6
SebriƩ, Ernesto Marcelo; Sandoya, Edgardo; Bianco, Eduardo et al. (2014) Hospital admissions for acute myocardial infarction before and after implementation of a comprehensive smoke-free policy in Uruguay: experience through 2010. Tob Control 23:471-2
Guindon, G Emmanuel; Driezen, Pete; Chaloupka, Frank J et al. (2014) Cigarette tax avoidance and evasion: findings from the International Tobacco Control Policy Evaluation (ITC) Project. Tob Control 23 Suppl 1:i13-22
Partos, Timea R; Borland, Ron; Thrasher, James F et al. (2014) The predictive utility of micro indicators of concern about smoking: findings from the International Tobacco Control Four Country study. Addict Behav 39:1235-42

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