The bioinformatics core will provide the resources and expertise necessary to integrate, analyze and share data generated by each of the three projects. Due to the inter-related nature of these projects and the large amount of data that will be generated in the genomics analyses of cancer stem cells, the core will be crucial to overall success of this proposal. It will provide a consistent and principled analysis framework for synthesizing high-dimensional data into biologically meaningful results. The bioinformatics core will be responsible for analyzing, sharing, and storing several forms of data, including genome sequence, genomewide expression measurements, and genome-wide DNA binding site information. The core's actions upon receiving these data will involve analysis using existing bioinformatics methods, development and application of novel methods, and data sharing and storage. The unique tools and resources of this core such as analytical programs developed by the Altman laboratory and access to the Clark Center supercomputer will be heavily used by all 3 projects in this proposal.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA139490-04
Application #
8375336
Study Section
Special Emphasis Panel (ZCA1-SRRB-C)
Project Start
Project End
Budget Start
2012-05-01
Budget End
2013-04-30
Support Year
4
Fiscal Year
2012
Total Cost
$122,378
Indirect Cost
$44,362
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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