The overall scientific goal of this ambitious Program Project is to develop innovative statistical methods for cancer clinical trials that can help to hasten successful introduction of effective new therapies into practice The Computational Resource and Dissemination Core (Core C) will carry out several critical functions related to the implementation and dissemination of the statistical methods for the design and analysis of cancer clinical trials developed in the five research projects. The Core will be tasked with developing, in close collaboration with project investigators, efficient, robust code implementing the statistical methods that can be used for evaluation of the methods in extensive simulation studies and for application of the methods to data compiled by Core B and from other sources. The Core will also be tasked with leading and facilitating, in close collaboration with project investigators, development of robust, reliable, user-friendly, and welldocumented software applications suitable for public dissemination to practitioners involved in the design and analysis of cancer clinical trials. Core C wili adopt best practices for these tasks and provide the necessary information technology and educational infrastructure to disseminate these applications.

Public Health Relevance

Before the new statistical methods for design and analysis of cancer clinical trials to be developed in this Program Project can be adopted for use in cancer research, they must be tested and evaluated, and they must be implemented in user-friendly software accessible to practitioners. Core C will collaborate closely with project investigators to facilitate these efforts.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA142538-04
Application #
8462936
Study Section
Special Emphasis Panel (ZCA1-RPRB-7)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
4
Fiscal Year
2013
Total Cost
$268,300
Indirect Cost
$38,297
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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