The Analytical Core led by Dr. Hongyu Zhao will support the statistics, bioinformatics, implementation, and data analysis needs of all the Projects of this Program Project. In coordination with the Administrative Core led by Dr. Yung-Chi Cheng, this Core will function to conduct statistical analysis of the clinical trial data from Project 1, assist in the analysis of potential biomarkers and their associations with patient responses from Project 2, and implement and apply the novel statistical methods to be developed in Project 3. This Core will also provide a training environment for program project personnel on software tools on data analysis and interpretation.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA154295-03
Application #
8567984
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
3
Fiscal Year
2013
Total Cost
$148,949
Indirect Cost
$50,533
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Zhu, Ruoqing; Zhao, Ying-Qi; Chen, Guanhua et al. (2017) Greedy outcome weighted tree learning of optimal personalized treatment rules. Biometrics 73:391-400
Sun, Jiehuan; Herazo-Maya, Jose D; Kaminski, Naftali et al. (2017) A Dirichlet process mixture model for clustering longitudinal gene expression data. Stat Med 36:3495-3506
Chao, Jung; Dai, Yuntao; Cheng, Hao-Yuan et al. (2017) Improving the Concentrations of the Active Components in the Herbal Tea Ingredient, Uraria crinita: The Effect of Post-harvest Oven-drying Processing. Sci Rep 7:38763
Lin, Zhixiang; Wang, Tao; Yang, Can et al. (2017) On joint estimation of Gaussian graphical models for spatial and temporal data. Biometrics 73:769-779
Sun, Jiehuan; Warren, Joshua L; Zhao, Hongyu (2017) A Bayesian semiparametric factor analysis model for subtype identification. Stat Appl Genet Mol Biol 16:145-158
Wang, Ying; Lam, Wing; Chen, Shao-Ru et al. (2016) Tylophorine Analog DCB-3503 Inhibited Cyclin D1 Translation through Allosteric Regulation of Heat Shock Cognate Protein 70. Sci Rep 6:32832
Lin, Zhixiang; Li, Mingfeng; Sestan, Nenad et al. (2016) A Markov random field-based approach for joint estimation of differentially expressed genes in mouse transcriptome data. Stat Appl Genet Mol Biol 15:139-50
Hu, Yiming; Zhao, Hongyu (2016) CCor: A whole genome network-based similarity measure between two genes. Biometrics 72:1216-1225
Lin, Zhixiang; Yang, Can; Zhu, Ying et al. (2016) Simultaneous dimension reduction and adjustment for confounding variation. Proc Natl Acad Sci U S A 113:14662-14667
Li, Cong; Yang, Can; Hather, Greg et al. (2016) Efficient Drug-Pathway Association Analysis via Integrative Penalized Matrix Decomposition. IEEE/ACM Trans Comput Biol Bioinform 13:531-40

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