The role of the Administrative Core in this Program is to facilitate the science, manage all aspects of the finances, and provide oversight for compliance. As the Core Leader, Dr. Nishimura has established a group of External Advisors which consists of outstanding scientists with unique expertise in each area of the Program. This includes general tumor immunology, T cell biology, TCR gene transfer, autoimmunity against melanocytes, adoptive T cell transfer clinical trial and biostatistics. Also, he has assembled a group of internal advisors with specific scientific, program project, and administrative expertise to assist with the management ofthe Program. And finally, Dr. Nishimura has assembled an administrative staff with expertise in procurement, grants accounting/management, and compliance to manage the Program. These functions are essential to the smooth operation ofthe Program.

Public Health Relevance

This Core will provide administrative support for the entire Program. This includes facilitating the research, purchasing of supplies, accounting, compliance oversight, and general administrative assistance.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA154778-03
Application #
8744937
Study Section
Special Emphasis Panel (ZCA1-RPRB-J (M1))
Project Start
2013-09-04
Project End
2016-08-31
Budget Start
2013-09-04
Budget End
2014-08-31
Support Year
3
Fiscal Year
2013
Total Cost
$96,631
Indirect Cost
$65,512
Name
Loyola University Chicago
Department
Type
DUNS #
791277940
City
Maywood
State
IL
Country
United States
Zip Code
60153
Chiuzan, Cody; Garrett-Mayer, Elizabeth; Yeatts, Sharon D (2015) A likelihood-based approach for computing the operating characteristics of the 3+3 phase I clinical trial design with extensions to other A+B designs. Clin Trials 12:24-33
Eby, Jonathan M; Kang, Hee-Kap; Klarquist, Jared et al. (2014) Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation. Pigment Cell Melanoma Res 27:1075-85
Kesarwani, Pravin; Al-Khami, Amir A; Scurti, Gina et al. (2014) Promoting thiol expression increases the durability of antitumor T-cell functions. Cancer Res 74:6036-47
Chatterjee, Shilpak; Thyagarajan, Krishnamurthy; Kesarwani, Pravin et al. (2014) Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors. Cancer Res 74:6048-59
Husain, Shahid; Abdul, Yasir; Webster, Christine et al. (2014) Interferon-gamma (IFN-?)-mediated retinal ganglion cell death in human tyrosinase T cell receptor transgenic mouse. PLoS One 9:e89392
Chatterjee, Shilpak; Eby, Jonathan M; Al-Khami, Amir A et al. (2014) A quantitative increase in regulatory T cells controls development of vitiligo. J Invest Dermatol 134:1285-94
Kohlhapp, Frederick J; Zloza, Andrew; O'Sullivan, Jeremy A et al. (2012) CD8(+) T cells sabotage their own memory potential through IFN-?-dependent modification of the IL-12/IL-15 receptor ? axis on dendritic cells. J Immunol 188:3639-47