The administrative core manages the overall organization of the project, and is responsible for project progress and budgetary reporting to NIH through annual progress reports and other mechanisms. The purposes of the administrative core are to coordinate the efforts of the individual groups, fostering communication and cooperation, and to ensure equitable access of each project to the shared resources provided by the virology core. To this end, the administrative core organizes monthly meetings of the project team where scientific progress is reported and other business discussed. This core also maintains an electronic bulletin board for the groups, which facilitates and enhances communication among project participants. Papers submitted for publication by project leaders are also distributed among the members of the project on a regular basis through the administrative core, providing a mechanism for team input. This core also organizes the annual review of the overall project by the advisory committees.

Public Health Relevance

The administrative core organizes a research project involving multidisciplinary team of investigators to address fundamental questions in 'novel immune mechanisms against herpes viruses. The knowledge gained by these research projects is relevant to the prevention and control of human herpesviruses.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
1P01CA177322-01A1
Application #
8660817
Study Section
Special Emphasis Panel (ZCA1-RPRB-J (O1))
Project Start
2014-09-19
Project End
2019-08-31
Budget Start
2014-09-19
Budget End
2015-08-31
Support Year
1
Fiscal Year
2014
Total Cost
$90,208
Indirect Cost
$10,147
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Koh, Mei Yee; Gagea, Mihai; Sargis, Timothy et al. (2016) A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice. Hepatology 63:1576-91
Xiong, Xiao-Peng; Kurthkoti, Krishna; Chang, Kung-Yen et al. (2016) miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila. PLoS Pathog 12:e1006034
Gong, Danyang; Kim, Yong Hoon; Xiao, Yuchen et al. (2016) A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export. Cell Host Microbe 20:642-653
Ward-Kavanagh, Lindsay K; Lin, Wai Wai; Šedý, John R et al. (2016) The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses. Immunity 44:1005-19
Scarzello, Anthony J; Jiang, Qun; Back, Timothy et al. (2016) LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours. Gut 65:1765-75
Feng, Jiaying; Gong, Danyang; Fu, Xudong et al. (2015) M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Sci Rep 5:17228
Shah, Priya S; Wojcechowskyj, Jason A; Eckhardt, Manon et al. (2015) Comparative mapping of host-pathogen protein-protein interactions. Curr Opin Microbiol 27:62-8
York, Autumn G; Williams, Kevin J; Argus, Joseph P et al. (2015) Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. Cell 163:1716-29
Lau, E; Sedy, J; Sander, C et al. (2015) Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy. Oncogene 34:5739-48
Davis, Zoe H; Verschueren, Erik; Jang, Gwendolyn M et al. (2015) Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Mol Cell 57:349-60

Showing the most recent 10 out of 13 publications