The administrative core manages the overall organization of the project, and is responsible for project progress and budgetary reporting to NIH through annual progress reports and other mechanisms. The purposes of the administrative core are to coordinate the efforts of the individual groups, fostering communication and cooperation, and to ensure equitable access of each project to the shared resources provided by the virology core. To this end, the administrative core organizes monthly meetings of the project team where scientific progress is reported and other business discussed. This core also maintains an electronic bulletin board for the groups, which facilitates and enhances communication among project participants. Papers submitted for publication by project leaders are also distributed among the members of the project on a regular basis through the administrative core, providing a mechanism for team input. This core also organizes the annual review of the overall project by the advisory committees.
The administrative core organizes a research project involving multidisciplinary team of investigators to address fundamental questions in 'novel immune mechanisms against herpes viruses. The knowledge gained by these research projects is relevant to the prevention and control of human herpesviruses.
|Šedý, John R; Balmert, M Olivia; Ware, Brian C et al. (2017) A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator. J Biol Chem 292:21060-21070|
|Yau, Edwin H; Kummetha, Indrasena Reddy; Lichinchi, Gianluigi et al. (2017) Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers. Cancer Res 77:6330-6339|
|Gong, Danyang; Dai, Xinghong; Xiao, Yuchen et al. (2017) Virus-Like Vesicles of Kaposi's Sarcoma-Associated Herpesvirus Activate Lytic Replication by Triggering Differentiation Signaling. J Virol 91:|
|Du, Yushen; Chi, Xiumei; Wang, Chong et al. (2017) Quantifying perinatal transmission of Hepatitis B viral quasispecies by tag linkage deep sequencing. Sci Rep 7:10168|
|Du, Yushen; Zhang, Tian-Hao; Dai, Lei et al. (2017) Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. MBio 8:|
|Dai, Xinghong; Li, Zhihai; Lai, Mason et al. (2017) In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. Nature 541:112-116|
|Xiong, Xiao-Peng; Kurthkoti, Krishna; Chang, Kung-Yen et al. (2016) miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila. PLoS Pathog 12:e1006034|
|Gong, Danyang; Kim, Yong Hoon; Xiao, Yuchen et al. (2016) A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export. Cell Host Microbe 20:642-653|
|Du, Yushen; Wu, Nicholas C; Jiang, Lin et al. (2016) Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis. MBio 7:|
|Scarzello, Anthony J; Jiang, Qun; Back, Timothy et al. (2016) LT?R signalling preferentially accelerates oncogenic AKT-initiated liver tumours. Gut 65:1765-75|
Showing the most recent 10 out of 21 publications