RESEARCH SUPPORT SUMMARY The sharing of strengths encouraged by the NIDA Program Project funding mechanism provides for greater opportunities and capabilities through the unification of a shared commitment to a central hypothetical question than would exist for any of the scientists involved individually. The main goal of the Administrative Core of this Proposal is to facilitate and support the unification and interaction of the scientists and administrative personnel working on the three Projects and two Cores of the Program Project Grant at The Rockefeller University and Yale University on this Proposal. The Administrative Core (AC) team have successfully supported the work of the researchers on this Program Project Grant for the last 14 years. Their combined expertise along with the flexibility to adapt to the changing needs of the researchers has led to the development of a proven set of methods for carrying out Specific Aims to aid the studies proposed. Through Aim I. the AC staff will facilitate coordination and communication between the Cores and Projects in the Proposal and data sharing. The AC staff will also oversee maintenance of the physical working space, supplies and equipment for the Cores and Projects 1 and 2 (Aim 11). The staff will also maintain the data and reports of the progress generated under this proposal and provide clerical support (Aim III). The AC staff will continue to utilize their expertise to integrate the various components and individuals of this Program Project Grant to ensure achievement of the goals of this application.

Public Health Relevance

Administrative Core staff will utilize their combined organizational and administrative expertise to support the integration of the researchers and institutions involved in this Program Project Grant Proposal. They will facilitate the communication, maintenance and reporting requirements of the Proposal allowing the investigators to focus on the research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Program Projects (P01)
Project #
5P01DA010044-19
Application #
8624678
Study Section
Special Emphasis Panel (ZRG1-MDCN-G)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
19
Fiscal Year
2014
Total Cost
$57,291
Indirect Cost
$23,391
Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Milosevic, Ana; Liebmann, Thomas; Knudsen, Margarete et al. (2016) Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain. J Comp Neurol :
Virk, Michael S; Sagi, Yotam; Medrihan, Lucian et al. (2016) Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum. Proc Natl Acad Sci U S A 113:734-9
Rapanelli, Maximiliano; Frick, Luciana R; Horn, Kyla D et al. (2016) The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons. J Biol Chem 291:21042-21052
Liu, Ruijie; Correll, Robert N; Davis, Jennifer et al. (2015) Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations. J Mol Cell Cardiol 87:204-13
Uematsu, Ken; Heiman, Myriam; Zelenina, Marina et al. (2015) Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function. J Neurochem 132:677-86
Engmann, Olivia; Giralt, Albert; Gervasi, Nicolas et al. (2015) DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons. Nat Commun 6:10099
Lee, K-W; Westin, L; Kim, J et al. (2015) Alteration by p11 of mGluR5 localization regulates depression-like behaviors. Mol Psychiatry 20:1546-56
Yamagata, Yoko; Nairn, Angus C (2015) Contrasting features of ERK1/2 activity and synapsin I phosphorylation at the ERK1/2-dependent site in the rat brain in status epilepticus induced by kainic acid in vivo. Brain Res 1625:314-23
Plattner, Florian; Hayashi, Kanehiro; Hernández, Adan et al. (2015) The role of ventral striatal cAMP signaling in stress-induced behaviors. Nat Neurosci 18:1094-100
Colangelo, Christopher M; Ivosev, Gordana; Chung, Lisa et al. (2015) Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics 15:1202-14

Showing the most recent 10 out of 194 publications