The proposed research has two specific aims: (1) to continue our five-year prospective assessment of the incidence of noncompliance among kidney transplant patients; and (2) to develop and evaluate survey-based intervention strategies aimed at reducing noncompliance in a sample of kidney transplant patients. We propose to continue our prospective chart study for the entire grant period, collecting and monitoring the kinds of medical history and self-report data that we have built into a nationally unique scientific database. This database has enabled our research team to track the differential predictors of noncompliance post-transplant, and to use that knowledge to develop and evaluate a patient education intervention. We also propose to develop and evaluate the use of survey interventions that will be specifically targeted at the underlying psychological bases of noncompliance. Social psychological research on persuasion suggest that persuasion is maximized when the persuasive appear matches the underlying cognitive or affective basis for the problem attitude and/or behavior. Two samples of transplant patients will be interviewed during the course of this intervention study. First, a cross sectional sample of transplant patient who participated in our patient education intervention study will be interviewed three times by telephone in Year 1. In addition, during year 1, we will begin to collect data on a longitudinal sample. Patients transplanted 9/1/96 and thereafter, will be interviewed in order to design an appropriate intervention strategy beginning one year after their transplant date. For example, patients whose chart and intervention study data suggests an emotional basis for noncompliance will receive, via intervention surveys three times a year, an emotion-based appear to improve compliance. elf-report and chart based measures will be used to assess patient compliance rates over time.

Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
33
Fiscal Year
2001
Total Cost
$185,017
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Matas, Arthur J; Vock, David M; Ibrahim, Hassan N (2018) GFR ?25 years postdonation in living kidney donors with (vs. without) a first-degree relative with ESRD. Am J Transplant 18:625-631
Sanchez, Otto A; Ferrara, Laine K; Rein, Sarah et al. (2018) Hypertension after kidney donation: Incidence, predictors, and correlates. Am J Transplant 18:2534-2543
Berglund, Danielle M; Zhang, Lei; Matas, Arthur J et al. (2018) Measured Glomerular Filtration Rate After Kidney Donation: No Evidence of Accelerated Decay. Transplantation 102:1756-1761
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Serrano, Oscar Kenneth; Kandaswamy, Raja; Gillingham, Kristen et al. (2017) Rapid Discontinuation of Prednisone in Kidney Transplant Recipients: 15-Year Outcomes From the University of Minnesota. Transplantation 101:2590-2598
Ibrahim, H N; Berglund, D M; Jackson, S et al. (2017) Renal Consequences of Diabetes After Kidney Donation. Am J Transplant 17:3141-3148
Gross, Cynthia R; Reilly-Spong, Maryanne; Park, Taehwan et al. (2017) Telephone-adapted Mindfulness-based Stress Reduction (tMBSR) for patients awaiting kidney transplantation. Contemp Clin Trials 57:37-43
Ibrahim, Hassan N; Foley, Robert N; Reule, Scott A et al. (2016) Renal Function Profile in White Kidney Donors: The First 4 Decades. J Am Soc Nephrol 27:2885-93
Verghese, Priya; Gillingham, Kristen; Matas, Arthur et al. (2016) Post-transplant blood transfusions and pediatric renal allograft outcomes. Pediatr Transplant 20:939-945

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