The Administrative Core is responsible for the day-to-day management of all administrative and financial aspects of the program project as well as the coordination and integration of program components. In addition, it fosters effective interactions between Program Project Principal Investigators and co-workers. Core A, ensures through the Steering Committee, that the services of scientific Core B are prioritized and effective in providing state-of-the-art technology, collaboration and guidance to Program Project Investigators. The core also administers the program of visiting scientists and consultants, a weekly seminar program, an annual mucosal immunology symposium and the yearly visit of the External Advisory Committee which enhances the programs goals of maintaining a creative, dynamic and productive scientific environment. Core A is also responsible for maintaining and implementing a relationship with research administrators at Harvard Medical School, Massachusetts General Hospital, Beth Israel Deaconess Medical Center and the Departments of Microbiology at the University of Massachusetts and Division of Gastroenterology in the Department of Medicine at UCLA. The Grants and Contracts Coordinator in charge of the core is responsible for following HMS regulations and those of the NIDDK including annual reports and non-competing renewal submissions. These duties are handled through the Executive Steering Committee and the Grants and Contracts Administrator to assure smooth oversight of the projects and locations in three different academic centers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK033506-29
Application #
8727519
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
29
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Hoffman, Jill M; Baritaki, Stavroula; Ruiz, Jonathan J et al. (2016) Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. Am J Pathol 186:134-44
Giannogonas, Panagiotis; Apostolou, Athanasia; Manousopoulou, Antigoni et al. (2016) Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy. Sci Rep 6:23342
Gregory, Katherine E; Samuel, Buck S; Houghteling, Pearl et al. (2016) Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants. Microbiome 4:68
Saslowsky, David E; Thiagarajah, Jay R; McCormick, Beth A et al. (2016) Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion. Mol Biol Cell 27:1120-30
Houghteling, Pearl D; Walker, W Allan (2015) From Birth to ""Immunohealth,"" Allergies and Enterocolitis. J Clin Gastroenterol 49 Suppl 1:S7-S12
O'Keeffe, Michael S; Song, Joo-Hye; Liao, Gongxian et al. (2015) SLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine. Gastroenterology 148:991-1001.e4
Zhou, Yanjiao; Shan, Gururaj; Sodergren, Erica et al. (2015) Longitudinal analysis of the premature infant intestinal microbiome prior to necrotizing enterocolitis: a case-control study. PLoS One 10:e0118632
Walker, W Allan; Iyengar, Rajashri Shuba (2015) Breast milk, microbiota, and intestinal immune homeostasis. Pediatr Res 77:220-8
Ganguli, Kriston; Collado, Maria C; Rautava, Jaana et al. (2015) Lactobacillus rhamnosus GG and its SpaC pilus adhesin modulate inflammatory responsiveness and TLR-related gene expression in the fetal human gut. Pediatr Res 77:528-35
Meng, Di; Zhu, Weishu; Shi, Hai Ning et al. (2015) Toll-like receptor-4 in human and mouse colonic epithelium is developmentally regulated: a possible role in necrotizing enterocolitis. Pediatr Res 77:416-24

Showing the most recent 10 out of 265 publications