This core provides administrative structure for the Program Project. Coe is responsible for all aspects of scientific quality, informational exchange, rate of work, collaboration and meetings. This core contains the clinical and research databases of the Kidney Stone Prevention Program. Data is gathered and consolidated from all Projects, stored and analyzed. This core also provides for statistical design and consulting for all Projects by Daniel Gillen. Coordination for the complex patient studies that involve recruitment and scheduling of patients across institutions is facilitated by a study coordinator who will also help maintain the study database.

Public Health Relevance

The studies proposed in this PPG require expert coordination and cooperation across the participating institutions. Carrying out the aims for the individual projects and especially the project aims of the overall PPG will often require input from several sources, including both laboratory cores and more than one project. The administrative core facilitates planning, execution, and analysis of these ambitious studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
2P01DK056788-11A1
Application #
8231136
Study Section
Special Emphasis Panel (ZDK1-GRB-R (M2))
Project Start
2011-09-20
Project End
2016-07-30
Budget Start
2011-09-20
Budget End
2012-07-31
Support Year
11
Fiscal Year
2011
Total Cost
$184,832
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Winfree, Seth; Khan, Shehnaz; Micanovic, Radmila et al. (2017) Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells. J Am Soc Nephrol 28:2108-2118
Winfree, Seth; Ferkowicz, Michael J; Dagher, Pierre C et al. (2017) Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications. Transl Res 189:1-12
Williams Jr, James C; Worcester, Elaine; Lingeman, James E (2017) What can the microstructure of stones tell us? Urolithiasis 45:19-25
Borofsky, Michael S; Paonessa, Jessica E; Evan, Andrew P et al. (2016) A Proposed Grading System to Standardize the Description of Renal Papillary Appearance at the Time of Endoscopy in Patients with Nephrolithiasis. J Endourol 30:122-7
Coe, Fredric L; Worcester, Elaine M; Evan, Andrew P (2016) Idiopathic hypercalciuria and formation of calcium renal stones. Nat Rev Nephrol 12:519-33
Borofsky, Michael S; Wollin, Daniel A; Reddy, Thanmaya et al. (2016) Salvage Percutaneous Nephrolithotomy: Analysis of Outcomes following Initial Treatment Failure. J Urol 195:977-81
Handa, Rajash K; Lingeman, James E; Bledsoe, Sharon B et al. (2016) Intraluminal measurement of papillary duct urine pH, in vivo: a pilot study in the swine kidney. Urolithiasis 44:211-7
Hoover, Robert S; Tomilin, Viktor; Hanson, Lauren et al. (2016) PTH modulation of NCC activity regulates TRPV5 Ca2+ reabsorption. Am J Physiol Renal Physiol 310:F144-51
Witzmann, Frank A; Evan, Andrew P; Coe, Fredric L et al. (2016) Label-free proteomic methodology for the analysis of human kidney stone matrix composition. Proteome Sci 14:4
Ko, Benjamin; Bergsland, Kristin; Gillen, Daniel L et al. (2015) Sex differences in proximal and distal nephron function contribute to the mechanism of idiopathic hypercalcuria in calcium stone formers. Am J Physiol Regul Integr Comp Physiol 309:R85-92

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