The Administrative Core serves the function of ensuring that the Program Project and all of its component parts function smoothly. The Administrative Core assures compliance with all policies and procedures pertaining to lab safety, including required environmental health and safety training for all laboratory employees, blood borne pathogens, tuberculosis and infection control, health care worker/Joint Committee on Accreditation of Hospitals general safety, and the overall lab safety plan. If there are any new employees or changes in requirements for any policies or procedures, the Administrative Core assures completion of the appropriate training and orientation. This core insures that all HIPPA rules and regulations are followed, and that Institutional Review Board regulations, forms and updates are complied with. Further, the clinic where many of our patients are seen must follow OSHA and Joint Committee on Accreditation of Hospitals guidelines. The Administrative Core assures proper completion and compliance with all animal rights and IACUC forms. There are day-to-day issues pertaining to publications, mailings, and the intake and output of supplies that fall under the general purview of the Administrative Core. The Administrative Core monitors the overall budget and the budget for each of the projects and cores for accurate accountability, to assure that personnel are appropriately compensated, and to ensure that there is adequate disbursement of funds for supplies and equipment as necessary.

Public Health Relevance

Core B provides centralized administrative support, human subjects policy, lab safety and animal welfare oversight to all 4 of the proposed research projects and Core A of the Program Project ANCA Glomerulonephritis: from Molecules to Man.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK058335-13
Application #
8566061
Study Section
Special Emphasis Panel (ZDK1-GRB-R (M1))
Project Start
2000-09-01
Project End
2015-07-31
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
13
Fiscal Year
2012
Total Cost
$67,282
Indirect Cost
$21,821
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Cortazar, Frank B; Pendergraft 3rd, William F; Wenger, Julia et al. (2017) Effect of Continuous B Cell Depletion With Rituximab on Pathogenic Autoantibodies and Total IgG Levels in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol 69:1045-1053
Jones, Britta E; Yang, Jiajin; Muthigi, Akhil et al. (2017) Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis. J Am Soc Nephrol 28:1175-1187
Merkel, Peter A; Xie, Gang; Monach, Paul A et al. (2017) Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Arthritis Rheumatol 69:1054-1066
Mariani, Laura H; Pendergraft 3rd, William F; Kretzler, Matthias (2016) Defining Glomerular Disease in Mechanistic Terms: Implementing an Integrative Biology Approach in Nephrology. Clin J Am Soc Nephrol 11:2054-2060
Yang, Jiajin; Ge, Heng; Poulton, Caroline J et al. (2016) Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Clin Epigenetics 8:85
Zhu, Meng-Lei; Bakhru, Pearl; Conley, Bridget et al. (2016) Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator. Nat Commun 7:11350
Thrasher, Bradly J; Hong, Lee Kyung; Whitmire, Jason K et al. (2016) Epigenetic Dysfunction in Turner Syndrome Immune Cells. Curr Allergy Asthma Rep 16:36
Free, Meghan E; Falk, Ronald J (2016) The Search for a Biomarker of Relapse in ANCA-Associated Vasculitis. J Am Soc Nephrol 27:2551-3
Bakhru, Pearl; Su, Maureen A (2016) Estrogen turns down ""the AIRE"". J Clin Invest 126:1239-41
Rhee, Rennie L; Hogan, Susan L; Poulton, Caroline J et al. (2016) Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Renal Disease. Arthritis Rheumatol 68:1711-20

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