The Administrative Core serves all four Projects and the Animal Model Core of the Program Project providing coordination, communication services, financial and budgetary services, and other financial and administrative services to the individual Project directors. Coordination between the P.l. and the project directors is maintained and facilitated by administrative personnel. Core personnel arrange regular meetings of investigators and distribute pertinent scientific information, progress reports, and internal and external project reviews. Financial services include monitoring the budgets of the individual projects, providing investigators with financial information, approving expenditures and providing purchasing assistance, and consolidation and completion of progress reports. The Administrative Core also serves as the liaison for the scheduling of yearly Advisory Committee meetings.

Public Health Relevance

. Inflammatory Bowel Disease afflicts 1.4 million Americans. The Projects in this Program will increase our understanding of the immune and genetic mechanisms involved in IBD. This Core will provide necessary administrative support and coordination for the Program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK071176-10
Application #
8712467
Study Section
Special Emphasis Panel (ZDK1-GRB-7)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
10
Fiscal Year
2014
Total Cost
$59,161
Indirect Cost
$14,393
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Zhao, Qing; Harbour, Stacey N; Kolde, Raivo et al. (2017) Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota. J Immunol 199:312-322
Cao, Wei; Kayama, Hisako; Chen, Mei Lan et al. (2017) The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids. Immunity 47:1182-1196.e10
Tanner, Scott M; Daft, Joseph G; Hill, Stephanie A et al. (2016) Altered T-Cell Balance in Lymphoid Organs of a Mouse Model of Colorectal Cancer. J Histochem Cytochem 64:753-767
Daft, Joseph G; Lorenz, Robin G (2015) Role of the gastrointestinal ecosystem in the development of type 1 diabetes. Pediatr Diabetes 16:407-18
Harbour, Stacey N; Maynard, Craig L; Zindl, Carlene L et al. (2015) Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis. Proc Natl Acad Sci U S A 112:7061-6
Basu, Rajatava; Whitley, Sarah K; Bhaumik, Suniti et al. (2015) IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol 16:286-95
Hepworth, Matthew R; Fung, Thomas C; Masur, Samuel H et al. (2015) Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4? T cells. Science 348:1031-5
Pike, Brian L; Paden, Katie Ann; Alcala, Ashley N et al. (2015) Immunological Biomarkers in Postinfectious Irritable Bowel Syndrome. J Travel Med 22:242-50
Christmann, Benjamin S; Abrahamsson, Thomas R; Bernstein, Charles N et al. (2015) Human seroreactivity to gut microbiota antigens. J Allergy Clin Immunol 136:1378-86.e1-5
Singer, Jeffrey R; Weaver, Casey T (2015) Daughter's Tolerance of Mom Matters in Mate Choice. Cell 162:467-9

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