Resource Management and Biostatistics Core: Summary/Abstract The primary objective of the Resource Management and Biostatistics Core is to unify and integrate the expertise and science of the investigators and to coordinate activities of the Program to promote maximum efficiency of resource utilization and the highest quality of scientific output. The overarching goal of the Core is to establish and promote effective communications, interactions and work flow among the Program components. To this end, the major responsibility of this Core will be to develop and maintain a centralized web-based system for management and sharing of resources and research data generated in the Program (Aim 1);provide biostatistical support for all the projects and Cores of the Program (Aim 2);facilitate utilization of the Cores and other shared resources at participating institutions (Aim 3);enhance the scientific environment through organization of research meetings and seminars (Aim 4);perform the administrative functions of the Program (Aim 5). The efficient functioning of the Resource Management and Biostatistics Core is a key to the success of this NIDDK Program Project, providing for greater opportunities and capabilities through the unification of a shared commitment to the central scientific theme of the Program than would exist for any of the scientists involved individually.

Public Health Relevance

Resource Management and Biostatistics Core: Narrative The Resource Management and Biostatistics Core have the function of managing the cores and their resources to make sure that there is maximal efficiency and use by investigators in the Program. The core will also be responsible for all areas of communication including scientific and administrative meetings, storing and sharing of data between programs and development and maintenance of a Program website to further enhance communication and sharing of data. The core is also responsible for all biostatistical support for the projects including experimental design and data analysis functions.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Research Program Projects (P01)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Los Angeles
United States
Zip Code
Donahue, Timothy R; Dawson, David W (2016) Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality. Trends Endocrinol Metab 27:770-781
Birtolo, Chiara; Pham, Hung; Morvaridi, Susan et al. (2016) Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration. Am J Pathol :
Yuan, Jingzhen; Pandol, Stephen J (2016) PKD signaling and pancreatitis. J Gastroenterol 51:651-9
Principe, Daniel R; DeCant, Brian; Mascariñas, Emman et al. (2016) TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis. Cancer Res 76:2525-39
Birtolo, Chiara; Go, Vay Liang W; Ptasznik, Andrzej et al. (2016) Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas 45:21-31
(2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12:1-222
Moris, Maria; Dawson, David W; Jiang, Jennifer et al. (2016) Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study. Pancreas 45:1353-8
Zhong, Zhenyu; Umemura, Atsushi; Sanchez-Lopez, Elsa et al. (2016) NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria. Cell 164:896-910
Toste, Paul A; Nguyen, Andrew H; Kadera, Brian E et al. (2016) Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Mol Cancer Res 14:437-47
Setiawan, Veronica Wendy; Pandol, Stephen J; Porcel, Jacqueline et al. (2016) Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort. Clin Gastroenterol Hepatol :

Showing the most recent 10 out of 40 publications