Resource Management and Biostatistics Core: Summary/Abstract The primary objective of the Resource Management and Biostatistics Core is to unify and integrate the expertise and science of the investigators and to coordinate activities of the Program to promote maximum efficiency of resource utilization and the highest quality of scientific output. The overarching goal of the Core is to establish and promote effective communications, interactions and work flow among the Program components. To this end, the major responsibility of this Core will be to develop and maintain a centralized web-based system for management and sharing of resources and research data generated in the Program (Aim 1);provide biostatistical support for all the projects and Cores of the Program (Aim 2);facilitate utilization of the Cores and other shared resources at participating institutions (Aim 3);enhance the scientific environment through organization of research meetings and seminars (Aim 4);perform the administrative functions of the Program (Aim 5). The efficient functioning of the Resource Management and Biostatistics Core is a key to the success of this NIDDK Program Project, providing for greater opportunities and capabilities through the unification of a shared commitment to the central scientific theme of the Program than would exist for any of the scientists involved individually.

Public Health Relevance

Resource Management and Biostatistics Core: Narrative The Resource Management and Biostatistics Core have the function of managing the cores and their resources to make sure that there is maximal efficiency and use by investigators in the Program. The core will also be responsible for all areas of communication including scientific and administrative meetings, storing and sharing of data between programs and development and maintenance of a Program website to further enhance communication and sharing of data. The core is also responsible for all biostatistical support for the projects including experimental design and data analysis functions.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Research Program Projects (P01)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Los Angeles
United States
Zip Code
Yang, Zemin; Liu, Yu; Qin, Lan et al. (2017) Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases. Am J Pathol 187:781-797
Setiawan, Veronica Wendy; Monroe, Kristine R; Pandol, Stephen J (2017) Reply. Clin Gastroenterol Hepatol 15:1139
Messenger, Scott W; Jones, Elaina K; Holthaus, Conner L et al. (2017) Acute acinar pancreatitis blocks vesicle-associated membrane protein 8 (VAMP8)-dependent secretion, resulting in intracellular trypsin accumulation. J Biol Chem 292:7828-7839
Bustos, Victor; Pulina, Maria V; Kelahmetoglu, Yildiz et al. (2017) Bidirectional regulation of A? levels by Presenilin 1. Proc Natl Acad Sci U S A 114:7142-7147
Bustos, Victor; Pulina, Maria V; Bispo, Ashley et al. (2017) Phosphorylated Presenilin 1 decreases ?-amyloid by facilitating autophagosome-lysosome fusion. Proc Natl Acad Sci U S A 114:7148-7153
Eibl, Guido; Cruz-Monserrate, Zobeida; Korc, Murray et al. (2017) Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer. J Acad Nutr Diet :
Birtolo, Chiara; Pham, Hung; Morvaridi, Susan et al. (2017) Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration. Am J Pathol 187:146-155
Gorelick, Fred S; Lerch, Markus M (2017) Do Animal Models of Acute Pancreatitis Reproduce Human Disease? Cell Mol Gastroenterol Hepatol 4:251-262
Lew, Daniel; Afghani, Elham; Pandol, Stephen (2017) Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment. Dig Dis Sci 62:1702-1712
Lugea, Aurelia; Gerloff, Andreas; Su, Hsin-Yuan et al. (2017) The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells. Gastroenterology 153:1674-1686

Showing the most recent 10 out of 63 publications