The primary function of the Administrative Core is to provide centralized staff to unify the Center for Children's Environmental Health Research under the guidance of the Center Director and Associate Directors and to facilitate the coordination of the research projects to fulfill the Center's research goals. In addition, the Administrative Core will establish and manage the External Advisory Committee and coordinate scientific meetings within and outside the Center. The Administrative Core will also assist in the active engagement of the community with Center activities and organize Community Advisory Board meetings. The Administrative Core will support the career development of the New Investigator. The Pediatric Health Specialist, a member of the Administrative Core, will assist with the coordination and integration of scientific projects, and ensure that the scientific results can be translated into clinical and public health practice. Thus, the Administrative Core aims to provide oversight, coordination, and integration of Center Activities.
The specific aims of the core are: 1. To assist the Center Director and Associate Directors in coordinating Center administrative and logistic operations; 2. To be responsible for the financial management of the Center, ensuring that all agency and university guidelines are met; 3. To provide a direct liaison with NIEHS, EPA, and other participating institutions; 4. To manage the External Advisory Committee (EAC) and Community Advisory Board (CAB) activities and coordinate their meetings, and to assist in the organization of national and international meetings related to the Center's activities; 5. To track the progress of the Center through progress reports and other documentation; 6. To create and maintain publication, trainee, personnel, investigator address, and equipment inventory databases; 7. To maintain data management including computer and network support across Projects and Cores; 8. To coordinate and monitor the career development for the Faculty Development Investigator, and the training support for students and fellows involved in Center-affiliated research; 9. To provide support for the activities of the Pediatric Health Specialist in coordination and translation; 10. To support community engagement activities to assure a productive working relationship between the community and the Center; 11. To develop a Center resource sharing plan in concert with the Biorepository Core.

Public Health Relevance

This Children's Center for Environmental Health Research Program Project will examine a set of endocrine disrupting and neurotoxic chemicals to which children living in agricultural communities in California may be particularly exposed: DDT, Mn, and PBDEs. We will examine the pathways and levels of exposures to children, the effects of these exposures on their neurodevelopment and pubertal development, and possible epigenetic mechanisms of action of these compounds. The overall goal is to reduce children's exposures and the Administrative Core will coordinate these efforts.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Research Program Projects (P01)
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Special Emphasis Panel (ZES1-LKB-G)
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University of California Berkeley
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Huen, Karen; Calafat, Antonia M; Bradman, Asa et al. (2016) Maternal phthalate exposure during pregnancy is associated with DNA methylation of LINE-1 and Alu repetitive elements in Mexican-American children. Environ Res 148:55-62
Raanan, Rachel; Balmes, John R; Harley, Kim G et al. (2016) Decreased lung function in 7-year-old children with early-life organophosphate exposure. Thorax 71:148-53
Huen, Karen; Harley, Kim; Kogut, Katherine et al. (2016) DNA methylation of LINE-1 and Alu repetitive elements in relation to sex hormones and pubertal timing in Mexican-American children. Pediatr Res 79:855-62
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Davé, Veronica; Street, Kelly; Francis, Stephen et al. (2016) Bacterial microbiome of breast milk and child saliva from low-income Mexican-American women and children. Pediatr Res 79:846-54
Waters, Sara F; Boyce, W Thomas; Eskenazi, Brenda et al. (2016) The impact of maternal depression and overcrowded housing on associations between autonomic nervous system reactivity and externalizing behavior problems in vulnerable Latino children. Psychophysiology 53:97-104
Mora, Ana María; Oken, Emily; Rifas-Shiman, Sheryl L et al. (2016) Prenatal Exposure to Perfluoroalkyl Substances and Adiposity in Early and Mid-Childhood. Environ Health Perspect :
Lizarraga, Daneida; Huen, Karen; Combs, Mary et al. (2016) miRNAs differentially expressed by next-generation sequencing in cord blood buffy coat samples of boys and girls. Epigenomics 8:1619-1635
Verner, Marc-André; Gaspar, Fraser W; Chevrier, Jonathan et al. (2015) Increasing sample size in prospective birth cohorts: back-extrapolating prenatal levels of persistent organic pollutants in newly enrolled children. Environ Sci Technol 49:3940-8

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