The Administrative, Career Development and Research Integration Core (Core A) of the Children's Environmental Health and Disease Prevention Research Center at Dartmouth will foster the overall goals and objectives of the Center by providing the services necessary to: (1) plan, implement and evaluate education, training, mentoring and career development activities of junior investigators (2) support a Child Health Specialist to ensure the translation of Center activities to clinical and public health practice, (3) integrate and track the cross-disciplinary research, outreach and translation activities and effective use of state-of-the-art institutional resources, and shared databases, environmental and biologic specimens, and 4) coordinate Center communications, fiscal, compliance, reporting and overall center evaluation and perform administrative functions. The Core leadership will consist of a Director, Associate Director, and Children's Health Specialist. Directors of the Institute for Quantitative Biomedical Sciences and Center for Clinical Biomedical Informatics, a senior biostatistician, early career biostatistician, statistical analyst, database programmer, laboratory manager, assistant child health specialist and field staff will assist in carrying out the integrated research and coordination activities. An External Advisory Board of internationally, nationally and regionally recognized experts in children's environmental health and disease prevention will be established to provide consultation, oversight and evaluation to support the Center. The Core, in particular, the Children's Health Specialist will work closely with the Community Outreach and Translation Core on translational efforts and to identify future research needs of relevance to children's environmental health and disease prevention.

Public Health Relevance

The Core will serve as the central oversight and coordinating body for all executive, managerial and evaluation functions, communications with internal and external sources, career development, education and training programs, and support for integration of Center activities to ensure successful achievement of its goals.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Research Program Projects (P01)
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Special Emphasis Panel (ZES1-LKB-K (P0))
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Dartmouth College
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Appleton, Allison A; Lester, Barry M; Armstrong, David A et al. (2015) Examining the joint contribution of placental NR3C1 and HSD11B2 methylation for infant neurobehavior. Psychoneuroendocrinology 52:32-42
Armstrong, David A; Lesseur, Corina; Conradt, Elisabeth et al. (2014) Global and gene-specific DNA methylation across multiple tissues in early infancy: implications for children's health research. FASEB J 28:2088-97
Davis, Matthew A; Gilbert-Diamond, Diane; Karagas, Margaret R et al. (2014) A dietary-wide association study (DWAS) of environmental metal exposure in US children and adults. PLoS One 9:e104768
Nadeau, Kari C; Li, Zhigang; Farzan, Shohreh et al. (2014) In utero arsenic exposure and fetal immune repertoire in a US pregnancy cohort. Clin Immunol 155:188-97
Sverrisson, Einar F; Zens, Michael S; Fei, Dennis Liang et al. (2014) Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer. Urol Oncol 32:539-45
Paquette, Alison G; Marsit, Carmen J (2014) The developmental basis of epigenetic regulation of HTR2A and psychiatric outcomes. J Cell Biochem 115:2065-72
Lesseur, Corina; Armstrong, David A; Paquette, Alison G et al. (2014) Maternal obesity and gestational diabetes are associated with placental leptin DNA methylation. Am J Obstet Gynecol 211:654.e1-9
Davis, Matthew A; Li, Zhigang; Gilbert-Diamond, Diane et al. (2014) Infant toenails as a biomarker of in utero arsenic exposure. J Expo Sci Environ Epidemiol 24:467-73
Lesseur, Corina; Paquette, Alison G; Marsit, Carmen J (2014) Epigenetic Regulation of Infant Neurobehavioral Outcomes. Med Epigenet 2:71-79
Lesseur, Corina; Armstrong, David A; Murphy, Megan A et al. (2014) Sex-specific associations between placental leptin promoter DNA methylation and infant neurobehavior. Psychoneuroendocrinology 40:1-9

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