The overall goal ofthe Administrative Core (AC) is to'provide oversight, coordination and integration of Center activities.
The Specific Aims are to: (1) Coordinate and integrate the scientific aims ofthe Projects and Cores, track and evaluate progress and outputs, and ensure successful completion of all Center aims; (2) Manage resources to assure the needs and priorities of every Project and Cores are met;(3) Act as coordinating center by convening meetings of Project, Core, and subcontract investigators, organize External Advisory Committee, ensure timely translation of research findings, prepare Center-wide reports, and interface with NIEHS and EPA project officers;(4) Evaluate the progress and success ofthe career, development plan, with specific focus on the career development of Faculty Development Investigator;(5) Ensure quality control of all stages of research namely study design, establishment of standard operating procedures and study protocols, secure sample and data transfer and management, data analysis, and accurate interpretation and translation of research findings to academic, government, healthcare and community stakeholders. The AC will operate under the direction of the Core Co-Leaders, Consultant, and Pediatric Health Specialist in collaboration with Leaders of each Project and Core. The AC will ensure coordination of Center activities, manage resources across Projects and Cores, identify the most efficient use of infrastructure and communication and resolve needs as they arise, in order to increase the efficiency and productive output ofthe Center. AC Leaders will interact with the External Advisory Board to ensure the merit and value of all UM-CEHC elements to accomplish the overall Center aims. The Center Manager will prioritize coordination with the Community Outreach and Translation Core to optimize outreach and research translation to community stakeholders. Finally, the AC will oversee career development and training of New Investigators, particularly the UM-CEHC Co-lnvestigator designated as the Faculty Development Investigator. Career development and training activities will draw upon extensive institutional resources and will be fully integrated with the Center's Research Projects and Cores.

Public Health Relevance

The goal of the Administrative Core is to oversee, coordinate and integrate all Center activities in order to ensure realization of specific aims for each Research Project, the Data Management and Modeling Core and the Community Outreach and Translation Core. The Administrative Core will integrate career development and training with research and will actively engage the External Advisory Board to promote successful completion and translation of Center research.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Research Program Projects (P01)
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Special Emphasis Panel (ZES1-LKB-K)
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University of Michigan Ann Arbor
Ann Arbor
United States
Zip Code
Anzai, Álvaro; Marcondes, Rodrigo R; Gonçalves, Thiago H et al. (2017) Impaired branched-chain amino acid metabolism may underlie the nonalcoholic fatty liver disease-like pathology of neonatal testosterone-treated female rats. Sci Rep 7:13167
Perng, Wei; Hector, Emily C; Song, Peter X K et al. (2017) Metabolomic Determinants of Metabolic Risk in Mexican Adolescents. Obesity (Silver Spring) 25:1594-1602
Kochmanski, Joseph; Marchlewicz, Elizabeth H; Savidge, Matthew et al. (2017) Longitudinal effects of developmental bisphenol A and variable diet exposures on epigenetic drift in mice. Reprod Toxicol 68:154-163
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Perng, Wei; Fernandez, Carmen; Peterson, Karen E et al. (2017) Dietary Patterns Exhibit Sex-Specific Associations with Adiposity and Metabolic Risk in a Cross-Sectional Study in Urban Mexican Adolescents. J Nutr 147:1977-1985
Perng, Wei; Watkins, Deborah J; Cantoral, Alejandra et al. (2017) Exposure to phthalates is associated with lipid profile in peripubertal Mexican youth. Environ Res 154:311-317

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