The Illinois Community Outreach and Translation Core (COTC) serves as the organizing hub of information and emerging knowledge about the effects of chemical exposure and high fat diets on the developing child and adolescenL The COTC links scientific investigators ofthe University of Illinois Children's Environmental Center with community stakeholders including pediatricians, public health professionals, parenting groups, and policy makers. The scientific investigators and community stakeholders work together through a Community Advisory Board (CAB) who assist in knowledge translation through established principles of community based participatory research and community engagement. Evidence based knowledge about the effects of chemical exposure and high fat diets on the developing young child and adolescent will be disseminated through a national parenting website (Just-in-Time-Parenting), web-based seminars for health professionals, and two targeted conferences aimed at key stakeholders.
The Specific Aims ofthe COTC are to: 1. To develop a strong Community Outreach and Translation Core (COTC) that is informed by the Community Advisory Board (CAB) that works bi-directionally with the Pi's ofthe Center. The CAB and Pi's will work together using established principles of community based participatory research and community engagement. 2. To develop a dissemination plan of emerging knowledge about the effects of chemical exposure on the developing young child and adolescent through a national E-extension parenting web-site, web-based seminars for health professionals, and two conferences aimed at key stakeholders (early care and health care providers). The COTC will develop a set of web and mobile-ready materials describing the effects of chemical exposure and high fat diets on the developing child and adolescent. These materials will be evaluated in a series of focus groups and by the CAB for usefulness and knowledge gained prior to dissemination.

Public Health Relevance

Key stakeholders (pregnant women, parents, early care providers, health care providers) may protect the health of developing children and adolescents by gaining knowledge of emerging science ofthe effects of chemical exposure and high fat diets. The COTC will work with the Pi's in a bi-directional manner through the CAB to promote responsible dissemination of emerging science ofthe Illinois Children's Center.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES022848-02
Application #
8678919
Study Section
Special Emphasis Panel (ZES1-LWJ-K)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
2
Fiscal Year
2014
Total Cost
$73,414
Indirect Cost
$26,395
Name
University of Illinois Urbana-Champaign
Department
Type
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Zhou, Changqing; Gao, Liying; Flaws, Jodi A (2017) Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice. Toxicol Appl Pharmacol 318:49-57
Mahalingam, Sharada; Ther, Laura; Gao, Liying et al. (2017) The effects of in utero bisphenol A exposure on ovarian follicle numbers and steroidogenesis in the F1 and F2 generations of mice. Reprod Toxicol 74:150-157
Zhou, Changqing; Gao, Liying; Flaws, Jodi A (2017) Exposure to an Environmentally Relevant Phthalate Mixture Causes Transgenerational Effects on Female Reproduction in Mice. Endocrinology 158:1739-1754
Zhou, Changqing; Flaws, Jodi A (2017) Effects of an Environmentally Relevant Phthalate Mixture on Cultured Mouse Antral Follicles. Toxicol Sci 156:217-229
Barakat, Radwa; Lin, Po-Ching Patrick; Rattan, Saniya et al. (2017) Prenatal Exposure to DEHP Induces Premature Reproductive Senescence in Male Mice. Toxicol Sci 156:96-108
Berger, Amelia; Ziv-Gal, Ayelet; Cudiamat, Jonathan et al. (2016) The effects of in utero bisphenol A exposure on the ovaries in multiple generations of mice. Reprod Toxicol 60:39-52
Wise, Leslie M; Sadowski, Renee N; Kim, Taehyeon et al. (2016) Long-term effects of adolescent exposure to bisphenol A on neuron and glia number in the rat prefrontal cortex: Differences between the sexes and cell type. Neurotoxicology 53:186-192
Oakley, Oliver R; Kim, Kee Jun; Lin, Po-Ching et al. (2016) Estradiol Synthesis in Gut-Associated Lymphoid Tissue: Leukocyte Regulation by a Sexually Monomorphic System. Endocrinology 157:4579-4587
Li, Quanxi; Davila, Juanmahel; Kannan, Athilakshmi et al. (2016) Chronic Exposure to Bisphenol A Affects Uterine Function During Early Pregnancy in Mice. Endocrinology 157:1764-74
Strakovsky, Rita S; Wang, Huan; Engeseth, Nicki J et al. (2015) Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. Toxicol Appl Pharmacol 284:101-12

Showing the most recent 10 out of 18 publications