The Administrative &Biostatistics Core provides centralized scientific support and leadership that facilitates collaborations between the five Projects and the Mass Spectrometry Core. In addition, it maintains the overall focus of the Center. Dr. L. Jackson Roberts II, Principle Investigator, has primary responsibility for all aspects of the Center. The Administrative &Biostatistics Core will oversee all annual budgets, monitor expenses, and provide monthly statements of financial activity. Further, all Center-related meetings and travel will be organized and schieduled through this Core. These include a bimonthly steering committee meeting of all Project and Core Leaders to evaluate and discuss scientific progress, allocation of Core usage, and Center resources. Arrangements for the Oversight Committee and Scientific Advisory Committees meetings, planned for the second and fourth years of the Center period, as well as generation of materials to be reviewed, will be handled through the Administrative &Biostatistics Core. Additionally, this Core will organize and coordinate the annual retreat for Center participants and advisors. The Core will prepare and assemble materials required for the annual progress reports and will ensure all additional NIH and institutional reporting requirements concerning the Center's activities are fulfilled in a timely manner. The Administrative &Biostatistics Core will also house biostatistical support services for all members of the Center under the direction of biostatistician Dr. Yu Shyr.

Public Health Relevance

The Administrative &Biostatistics Core provides centralized scientific support and leadership that facilitates collaborations between the five Projects and the Mass Spectrometry Core. Biostatistics support is critical to the research studies proposed, to ensure that useful and usable data are generated and analyzed appropriately to meet study specific aims.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM015431-47
Application #
8690881
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
47
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37212
Teder, Tarvi; Boeglin, William E; Brash, Alan R (2017) Oxidation of C18 Hydroxy-Polyunsaturated Fatty Acids to Epoxide or Ketone by Catalase-Related Hemoproteins Activated with Iodosylbenzene. Lipids 52:587-597
Teder, Tarvi; Boeglin, William E; Schneider, Claus et al. (2017) A fungal catalase reacts selectively with the 13S fatty acid hydroperoxide products of the adjacent lipoxygenase gene and exhibits 13S-hydroperoxide-dependent peroxidase activity. Biochim Biophys Acta 1862:706-715
Plewes, Katherine; Kingston, Hugh W F; Ghose, Aniruddha et al. (2017) Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study. BMC Infect Dis 17:313
Kong, Deping; Li, Juanjuan; Shen, Yujun et al. (2017) Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1. J Pharmacol Exp Ther 360:435-444
Gamble-George, Joyonna Carrie; Baldi, Rita; Halladay, Lindsay et al. (2016) Cyclooxygenase-2 inhibition reduces stress-induced affective pathology. Elife 5:
Adeniji, Adegoke; Uddin, Md Jashim; Zang, Tianzhu et al. (2016) Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor. J Med Chem 59:7431-44
Kudalkar, Shalley N; Kingsley, Philip J; Marnett, Lawrence J (2016) Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. Methods Mol Biol 1412:205-15
Wu, Jing; Montaniel, Kim Ramil C; Saleh, Mohamed A et al. (2016) Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension. Hypertension 67:461-8
Harrison, D G; Guzik, Tomasz J (2016) Macrophages come to mind as keys to cognitive decline. J Clin Invest 126:4393-4395
Montaniel, Kim Ramil C; Harrison, David G (2016) Is Hypertension a Bone Marrow Disease? Circulation 134:1369-1372

Showing the most recent 10 out of 149 publications