Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
3P01GM039589-05S1
Application #
3096330
Study Section
Special Emphasis Panel (SRC (02))
Project Start
1987-09-01
Project End
1992-08-31
Budget Start
1991-09-30
Budget End
1992-08-31
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Arts and Sciences
DUNS #
071723621
City
Cambridge
State
MA
Country
United States
Zip Code
02138
Verdine, Gregory L; Norman, Derek P G (2003) Covalent trapping of protein-DNA complexes. Annu Rev Biochem 72:337-66
Abdulaev, Najmoutin G; Strassmaier, Timothy T; Ngo, Tony et al. (2002) Grafting segments from the extracellular surface of CCR5 onto a bacteriorhodopsin transmembrane scaffold confers HIV-1 coreceptor activity. Structure 10:515-25
Lin, C H; Hare, B J; Wagner, G et al. (2001) A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies. Mol Cell 8:581-90
Mantis, N J; Kozlowski, P A; Mielcarz, D W et al. (2001) Immunization of mice with recombinant gp41 in a systemic prime/mucosal boost protocol induces HIV-1-specific serum IgG and secretory IgA antibodies. Vaccine 19:3990-4001
Zhou, G; Ferrer, M; Chopra, R et al. (2000) The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg Med Chem 8:2219-27
Huang, H; Harrison, S C; Verdine, G L (2000) Trapping of a catalytic HIV reverse transcriptase*template:primer complex through a disulfide bond. Chem Biol 7:355-64
Ferrer, M; Harrison, S C (1999) Peptide ligands to human immunodeficiency virus type 1 gp120 identified from phage display libraries. J Virol 73:5795-802
Frankel, A D; Young, J A (1998) HIV-1: fifteen proteins and an RNA. Annu Rev Biochem 67:1-25
Huang, H; Chopra, R; Verdine, G L et al. (1998) Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science 282:1669-75
Weissenhorn, W; Calder, L J; Dessen, A et al. (1997) Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli. Proc Natl Acad Sci U S A 94:6065-9

Showing the most recent 10 out of 39 publications