This core provides the administrative leadership, management and oversight of the Program Project. The overall goal of this core is to ensure responsible and responsive management of the program as a whole, promote collaboration between the subprojects, and to aid in transparent dissemination of the program output (the Phenix software) to the research community. The Project Director will provide budget oversight for the whole project, set the scientific goals for the whole program in collaboration with the project PIs, ensure program milestones are met in a timely manner, assess the progress in the individual projects, make significant changes in program composition if necessary, and report progress to the NIH program manager. The Project Director will promote, monitor and evaluate collaboration between the subprojects. Finally, this core will continue to be responsible for providing easy to use web services for downloading the Phenix software.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
2P01GM063210-16
Application #
9209982
Study Section
Special Emphasis Panel (ZRG1-BCMB-X (40)P)
Project Start
Project End
Budget Start
2016-09-01
Budget End
2017-08-31
Support Year
16
Fiscal Year
2017
Total Cost
$74,516
Indirect Cost
Name
Lawrence Berkeley National Laboratory
Department
Type
Domestic for-Profits
DUNS #
078576738
City
Berkeley
State
CA
Country
United States
Zip Code
94720
Hintze, Bradley J; Richardson, Jane S; Richardson, David C (2017) Mismodeled purines: implicit alternates and hidden Hoogsteens. Acta Crystallogr D Struct Biol 73:852-859
Demydchuk, Mykhaylo; Hill, Chris H; Zhou, Aiwu et al. (2017) Insights into Hunter syndrome from the structure of iduronate-2-sulfatase. Nat Commun 8:15786
Richardson, Jane S; Videau, Lizbeth L; Williams, Christopher J et al. (2017) Broad Analysis of Vicinal Disulfides: Occurrences, Conformations with Cis or with Trans Peptides, and Functional Roles Including Sugar Binding. J Mol Biol 429:1321-1335
Greber, Basil J; Nguyen, Thi Hoang Duong; Fang, Jie et al. (2017) The cryo-electron microscopy structure of human transcription factor IIH. Nature 549:414-417
McCoy, Airlie J; Oeffner, Robert D; Wrobel, Antoni G et al. (2017) Ab initio solution of macromolecular crystal structures without direct methods. Proc Natl Acad Sci U S A 114:3637-3641
Zheng, Min; Reimers, Jeffrey R; Waller, Mark P et al. (2017) Q|R: quantum-based refinement. Acta Crystallogr D Struct Biol 73:45-52
Hryc, Corey F; Chen, Dong-Hua; Afonine, Pavel V et al. (2017) Accurate model annotation of a near-atomic resolution cryo-EM map. Proc Natl Acad Sci U S A 114:3103-3108
Moriarty, Nigel W; Draizen, Eli J; Adams, Paul D (2017) An editor for the generation and customization of geometry restraints. Acta Crystallogr D Struct Biol 73:123-130
Liebschner, Dorothee; Afonine, Pavel V; Moriarty, Nigel W et al. (2017) Polder maps: improving OMIT maps by excluding bulk solvent. Acta Crystallogr D Struct Biol 73:148-157
Akey, David L; Terwilliger, Thomas C; Smith, Janet L (2016) Efficient merging of data from multiple samples for determination of anomalous substructure. Acta Crystallogr D Struct Biol 72:296-302

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