The purpose of the administrative core is to ensure optimal administrative cohesion between the three Projects and two scientific Cores. Dr. Tamm will be responsible for ensuring the coordination between these five components of the grant. He will devote 7.5% of his time to these efforts. He will be assisted by an administrative assistant (50% effort) who will help with all administrative issues regarding this Program Project. The Core will be responsible for organizing monthly local meetings and quarterly video conferences between the labs, and for organizing annual joint Program Project workshops. The Core will also coordinate meetings with members of the Scientific Advisory Board, and will be responsible for the execution of subcontracts to the components at the Max Planck Institute and coordinate regulatory issues between UVa and Max-Planck.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM072694-09
Application #
8706174
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
9
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
DUNS #
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Nyenhuis, Sarah B; Cafiso, David S (2018) Choice of reconstitution protocol modulates the aggregation state of full-length membrane-reconstituted synaptotagmin-1. Protein Sci 27:1008-1012
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Liang, Binyong; Tamm, Lukas K (2018) Solution NMR of SNAREs, complexin and ?-synuclein in association with membrane-mimetics. Prog Nucl Magn Reson Spectrosc 105:41-53
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Witkowska, Agata; Jablonski, Lukasz; Jahn, Reinhard (2018) A convenient protocol for generating giant unilamellar vesicles containing SNARE proteins using electroformation. Sci Rep 8:9422
Kiessling, Volker; Kreutzberger, Alex J B; Liang, Binyong et al. (2018) A molecular mechanism for calcium-mediated synaptotagmin-triggered exocytosis. Nat Struct Mol Biol 25:911-917
Kreutzberger, Alex J B; Kiessling, Volker; Liang, Binyong et al. (2017) Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability. Biophys J 113:1912-1915
Tamm, Lukas K (2017) Special Issue on Liposomes, Exosomes, and Virosomes. Biophys J 113:E1
Jakhanwal, Shrutee; Lee, Chung-Tien; Urlaub, Henning et al. (2017) An activated Q-SNARE/SM protein complex as a possible intermediate in SNARE assembly. EMBO J 36:1788-1802

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