The Molecular Biology Core provides service pertaining to cloning, sequencing and recombinant protein expression and characterization;measures fucosyl and sialyl histo-blood group antigens in samples to phenotype individuals in population and clinical human studies;conducts protein conjugation of synthetic oligosaccharide for preclinical studies;and performs and uses other diagnostic methods as appropriate. This core serves all projects.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD013021-35
Application #
8514658
Study Section
Special Emphasis Panel (ZHD1-DSR-A)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
35
Fiscal Year
2013
Total Cost
$111,278
Indirect Cost
$25,373
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
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Newburg, David S; Ko, Jae Sung; Leone, Serena et al. (2016) Human Milk Oligosaccharides and Synthetic Galactosyloligosaccharides Contain 3'-, 4-, and 6'-Galactosyllactose and Attenuate Inflammation in Human T84, NCM-460, and H4 Cells and Intestinal Tissue Ex Vivo. J Nutr 146:358-67
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Dai, Ying-Chun; Zhang, Xu-Fu; Xia, Ming et al. (2015) Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera. PLoS One 10:e0124945
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