Core A, the Administrative Core, will provide day-to-day scientific leadership and support for communicationbetween the Projects. The Core has four Specific Aims.
Aim 1. Scientific Leadership: The Core is headed by Carl A. Hubel, PhD. Since February 2006, Dr. Hubelhas been responsible for the overall planning, coordination, implementation and management of programactivities conducted at both the Pittsburgh and San Francisco sites, and for facilitating ongoingcommunications and interactions along Investigators and Clinical Core Staff. James M. Roberts. MD, theprevious Program Director and currently the PI of Project II and co-l on Core A and Core B of the currentcompetitive renewal application, will continue to assist Dr. Hubel in the transition of leadership. ArundhathiJeyabalan. MD. will assist Dr. Roberts and Dr. Hubel in integrating the Magee-Womens Hospital CentralData Repository into the mechanics of the PPG, to facilitate subproject collaborative integration of clinicaland laboratory data. Dr. Jeyabalan will also liaison/interface with activities of the Division of Maternal-FetalMedicine and the Magee-Womens Hospital arm of the NICHD MFMU Network. The Administrative Core willalso seek guidance from Internal and External Advisory Committees on a regular basis.
Aim 2. Communication/Conferences: The key role of the Administrative Core is to establish efficientcommunication as it relates to the dissemination of scientific ideas and data/discoveries. The Core organizesand prepares minutes for the Executive Committee meetings. In addition the Core is responsible fororganizing the yearly meetings with Dr. Fisher (UCSF, Project I) and the Advisory Committees. AllPittsburgh-based scientific Key Personnel have 'PPG meetings' organized by the Core on a regular basis toshare ideas, preliminary data, troubleshoot, and set direction for the upcoming months. The AdministrativeCore will pursue an active interaction with NIH and the office of Sponsored Programs. The AdministrativeCore will also coordinate the preparation of the progress reports for NIH. The Core will track publications andassure their proper acknowledgment of funding support.
Aim 3. IRB/IACUC/Safety: Because of the use of both Animals and Human tissues/cells this will necessitatere-approval and approval for modifications during the period of the grant from both the University ofPittsburgh IRB and the Animal Care and Use Committee/IACUC. Core A will provide administrativeassistance for preparation of these applications.
Aim 4. Budget Management: One major responsibility is to oversee the financial conduct of the overallProgram Project Grant.This is a small core but it has been vital to the success of the Program.
| Global Pregnancy Collaboration:; Schalekamp-Timmermans, Sarah; Arends, Lidia R et al. (2017) Fetal sex-specific differences in gestational age at delivery in pre-eclampsia: a meta-analysis. Int J Epidemiol 46:632-642 |
| Hux, Vanessa J; Roberts, James M; Okun, Michele L (2017) Allostatic load in early pregnancy is associated with poor sleep quality. Sleep Med 33:85-90 |
| Countouris, Malamo E; Schwarz, Eleanor B; Rossiter, Brianna C et al. (2016) Effects of lactation on postpartum blood pressure among women with gestational hypertension and preeclampsia. Am J Obstet Gynecol 215:241.e1-8 |
| Gandley, Robin E; Althouse, Andrew; Jeyabalan, Arundhathi et al. (2016) Low Soluble Syndecan-1 Precedes Preeclampsia. PLoS One 11:e0157608 |
| Luiza, John W; Gallaher, Marcia J; Powers, Robert W (2015) Urinary cortisol and depression in early pregnancy: role of adiposity and race. BMC Pregnancy Childbirth 15:30 |
| Hux, Vanessa J; Roberts, James M (2015) A potential role for allostatic load in preeclampsia. Matern Child Health J 19:591-7 |
| Hassis, Maria E; Niles, Richard K; Braten, Miles N et al. (2015) Evaluating the effects of preanalytical variables on the stability of the human plasma proteome. Anal Biochem 478:14-22 |
| Catov, Janet M; Abatemarco, Diane; Althouse, Andrew et al. (2015) Patterns of gestational weight gain related to fetal growth among women with overweight and obesity. Obesity (Silver Spring) 23:1071-8 |
| Founds, Sandra A; Ren, Dianxu; Roberts, James M et al. (2015) Follistatin-like 3 across gestation in preeclampsia and uncomplicated pregnancies among lean and obese women. Reprod Sci 22:402-9 |
| Sween, Lindsay K; Althouse, Andrew D; Roberts, James M (2015) Early-pregnancy percent body fat in relation to preeclampsia risk in obese women. Am J Obstet Gynecol 212:84.e1-7 |
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