ProgramDirector/PrincipalInvestigator(Last,First,Middle): Thomburg,KL-CoreB Abstract This Program Project Grant designed an animal core to improve cost effectiveness and provide efficiency for the projects in the program. Projects I, 1,1 will all use sheep through the assistance of the core. The Animal Core provides many advantages for PPG investigators. First, it is much easier to schedule a time-mated breeding program with sheep suppliers, and less expensive by use ofthe "economy of scale." It would be chaotic to have every sheep investigator trying to buy sheep independently. Second, it is often possible to share tissues, and on occasion live animals with other investigators who need similariy instrumented animals for a slightly different purpose. Third, the Department of Comparative Medicine shares animal laboratories within the animal facility for the purpose of chronic experimentation. It would be difficult to overstate the convenience of not having to transport instrumented animals across campus, apart from the otherwise worrisome considerations of the transmission of zoonotic diseases. Fourth, many of the

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
2P01HD034430-16A1
Application #
8521765
Study Section
Special Emphasis Panel (ZHD1-DSR-Z (41))
Project Start
Project End
Budget Start
2013-06-07
Budget End
2014-03-31
Support Year
16
Fiscal Year
2013
Total Cost
$261,715
Indirect Cost
$91,770
Name
Oregon Health and Science University
Department
Type
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
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Chattergoon, Natasha N; Louey, Samantha; Stork, Philip et al. (2012) Mid-gestation ovine cardiomyocytes are vulnerable to mitotic suppression by thyroid hormone. Reprod Sci 19:642-9
Thornburg, Kent; Jonker, Sonnet; O'Tierney, Perrie et al. (2011) Regulation of the cardiomyocyte population in the developing heart. Prog Biophys Mol Biol 106:289-99

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