Aim 1: Provide Scientific Leadership: Scientific decision-making is the responsibility of the Project Director/Principle Investigator after consultation with the Project/Core leaders and discussion at our regular meetings linked with consensus building. The administrative Core will also be the interface and will seek guidance from the Internal and External Advisory Committees Aim 2: Communication/Conferences: The key role of the Administrative Core is to establish efficient communication as it relates to the dissemination of scientific data/discoveries. Our success will be dependent on the active and open communication process between the members of the POl at all levels. The Administrative Core will pursue an active interaction with the Internal and External Advisory Committees and NIH and the office of Sponsored Programs itself. At specific intervals we will have a "Strategic Meeting" to set the direction for the next Quarter and plan for the Internal and External Advisors visits. The administrative Core will also coordinate the preparation of the progress reports for NIH prior to the joint External/Internal Advisory Committee meetings.
Aim 3 : Budget Management: Oversee the financial and conduct of the overall POl. Projects leaders will have responsibility for managing their individual budgets, with summaries provided by Core A. Core A will prepare budget summaries for presentation to the Pi's and Core directors.
Aim 4 : IRB/IACUC/Safety: Helping with Animals and Human Subjects, and Safety Committees re-approval.

Public Health Relevance

The Administrative Core will continue provide leadership for the smooth conduct of the 3 projects and 2 cores. This includes facilitating proper communication within the PPG and with NIH and the University in general. To this end the model we have adhered to for the past 10 years has many proven strengths as demonstrated by the outstanding productivity of the POl to date. Division of Reproductive Sciences and our department have synergized with an excellent group of established scientists to ensure outstanding success.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
2P01HD038843-11A1
Application #
8616124
Study Section
Special Emphasis Panel (ZHD1-DSR-Z (MR))
Project Start
Project End
Budget Start
2013-08-15
Budget End
2014-05-31
Support Year
11
Fiscal Year
2013
Total Cost
$54,857
Indirect Cost
$18,407
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Schreier, David A; Forouzan, Omid; Hacker, Timothy A et al. (2016) Increased Red Blood Cell Stiffness Increases Pulmonary Vascular Resistance and Pulmonary Arterial Pressure. J Biomech Eng 138:021012
Ampey, Bryan C; Morschauser, Timothy J; Ramadoss, Jayanth et al. (2016) Domain-Specific Partitioning of Uterine Artery Endothelial Connexin43 and Caveolin-1. Hypertension 68:982-8
Pastore, Mayra B; Talwar, Saira; Conley, Meghan R et al. (2016) Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells. Biol Reprod 94:139
Rozner, Ann E; Durning, Maureen; Kropp, Jenna et al. (2016) Macrophages modulate the growth and differentiation of rhesus monkey embryonic trophoblasts. Am J Reprod Immunol 76:364-375
Li, Yan; Wang, Kai; Zou, Qing-Yun et al. (2015) 2,3,7,8-Tetrachlorodibenzo-p-dioxin differentially suppresses angiogenic responses in human placental vein and artery endothelial cells. Toxicology 336:70-8
Morris, Erin A; Hale, Sarah A; Badger, Gary J et al. (2015) Pregnancy induces persistent changes in vascular compliance in primiparous women. Am J Obstet Gynecol 212:633.e1-6
Boeldt, Derek S; Grummer, Mary A; Yi, FuXian et al. (2015) Phosphorylation of Ser-279/282 and Tyr-265 positions on Cx43 as possible mediators of VEGF-165 inhibition of pregnancy-adapted Ca2+ burst function in ovine uterine artery endothelial cells. Mol Cell Endocrinol 412:73-84
Li, Yan; Wang, Kai; Zou, Qing-Yun et al. (2015) A possible role of aryl hydrocarbon receptor in spontaneous preterm birth. Med Hypotheses 84:494-7
Ampey, Bryan; Bird, Ian; Magness, Ron (2015) [307-POS]: Cx43 phosphorylation and the functionality of Cx43 gap junctions are moderated by cyclic nucleotide activity in UAECs and HUVECs. Pregnancy Hypertens 5:151-2
Anaya, Heather A; Yi, Fu-Xian; Boeldt, Derek S et al. (2015) Changes in Ca2+ Signaling and Nitric Oxide Output by Human Umbilical Vein Endothelium in Diabetic and Gestational Diabetic Pregnancies. Biol Reprod 93:60

Showing the most recent 10 out of 72 publications