The primary objecfive of the Administrative Core is to provide overall administrative support to the program. This administrative support will include communicafion with the institufional administration, maintaining and distribufing records regarding the fiscal management of the grant, preparing annual program reports, and coordinafing the meefings of the advisory committees. In addifion, the Administrafive Core will maintain records of such things as IRB approvals, Institufional Animal Care and Use Committee approvals, and signed consent forms. Finally, the Core will provide data management and stafisfical support for all of the projects. These activities will be under the direction of Dr. James C. Rose and he will be advised at the monthly meetings of the project investigators concerning all aspects of progress on the project and administrative issues. The administrative team is made up of senior investigators and an administrative secretary with extensive experience in coordinafing and managing the acfivities of mulfidisciplinary groups. Ms. Melissa Whitson will assist Dr. Rose in these activities and Dr. Beveriy Snively will oversee the data analysis acfivities. The following speciflc objectives are proposed: 1) To promote efficient use of the PPG's resources;2) to promote the exchange of scientific ideas and data within not only the POl Working Group, made up of the Project Leaders, the Directors of the Cores, and the Co-investigators participating in this PPG, but also with the larger scientiflc community;3) to provide internal and external review of the progress made by the PPG and, 4) to provide experimental design and data analysis support for the project.

Public Health Relevance

Not applicable.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD047584-07
Application #
8381687
Study Section
Special Emphasis Panel (ZHD1-DSR-Z)
Project Start
Project End
2016-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
7
Fiscal Year
2012
Total Cost
$79,069
Indirect Cost
$25,691
Name
Wake Forest University Health Sciences
Department
Type
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157
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Chappell, Mark C; Al Zayadneh, Ebaa M (2017) Angiotensin-(1-7) and the Regulation of Anti-Fibrotic Signaling Pathways. J Cell Signal 2:
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Massmann, G Angela; Zhang, Jie; Seong, Won Joon et al. (2017) Sex-dependent effects of antenatal glucocorticoids on insulin sensitivity in adult sheep: role of the adipose tissue renin angiotensin system. Am J Physiol Regul Integr Comp Physiol 312:R1029-R1038
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South, Andrew M; Nixon, Patricia A; Chappell, Mark C et al. (2017) Antenatal corticosteroids and the renin-angiotensin-aldosterone system in adolescents born preterm. Pediatr Res 81:88-93
Su, Yixin; Bi, Jianli; Pulgar, Victor M et al. (2017) Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells. Am J Physiol Renal Physiol 312:F1056-F1062
Wilson, Bryan A; Chappell, Mark C (2017) Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria. Methods Mol Biol 1614:99-121
Nixon, Patricia A; Washburn, Lisa K; Michael O'Shea, Thomas et al. (2017) Antenatal steroid exposure and heart rate variability in adolescents born with very low birth weight. Pediatr Res 81:57-62

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