The advantage of the Reproductive Immunology Core Unit will be to centralize a number of techniques and services that are pivotal to all of the Program's projects. Through this, the Program will prove cost effective by saving significant funds with the bulk purchasing of tissue culture and other consumable components, as well as animal housing. The ability to consolidate this Core's purchasing will enable us to ask for tenders from individual companies who will be able to supply the majority of items needed. This method will lead to expected savings of at least 50%. In addition, the establishment of standing orders will streamline both ordering and receiving of products. Dr Abrahams and Dr Mor will meet regularly to ensure the efficient and cost-effective service of this Core Unit.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD054713-05
Application #
8473085
Study Section
Special Emphasis Panel (ZHD1-MCHG-B)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
5
Fiscal Year
2013
Total Cost
$202,430
Indirect Cost
$81,246
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
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Racicot, Karen; Kwon, Ja-Young; Aldo, Paulomi et al. (2014) Understanding the complexity of the immune system during pregnancy. Am J Reprod Immunol 72:107-16
Kwon, Ja-Young; Romero, Roberto; Mor, Gil (2014) New insights into the relationship between viral infection and pregnancy complications. Am J Reprod Immunol 71:387-90
Bakaysa, S L; Potter, J A; Hoang, M et al. (2014) Single- and double-stranded viral RNA generate distinct cytokine and antiviral responses in human fetal membranes. Mol Hum Reprod 20:701-8
Abrahams, Vikki M; Potter, Julie A; Bhat, Geeta et al. (2013) Bacterial modulation of human fetal membrane Toll-like receptor expression. Am J Reprod Immunol 69:33-40
Racicot, Karen; Cardenas, Ingrid; Wunsche, Vera et al. (2013) Viral infection of the pregnant cervix predisposes to ascending bacterial infection. J Immunol 191:934-41
Krikun, Graciela; Potter, Julie A; Abrahams, Vikki M (2013) Human endometrial endothelial cells generate distinct inflammatory and antiviral responses to the TLR3 agonist, Poly(I:C) and the TLR8 agonist, viral ssRNA. Am J Reprod Immunol 70:190-8

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