The overall goal of the Administrative Core is to provide administrative, fiscal and scientific management of this P01 program project grant. A key function of this Core will be to provide scientific leadership, including identifying opportunities for interaction and synergy among the projects. Additional objectives of this Core include: to provide biostatistical support for each of the scientific projects and to provide a contact for the NIH program staff and help facilitate interactions with NIH program leaders.

Public Health Relevance

(Seeinstructions): An active and responsive Administrative Core is critical to achieving the goals of the program grant;these include studies to identify risk factors for HIV-1 acquisition in women and studies to define the mechanisms that increase risk in women. Both are relevant to finding ways to decrease the burden of HIV-1 in women.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD064915-05
Application #
8500417
Study Section
Special Emphasis Panel (ZAI1-TP-A)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
5
Fiscal Year
2013
Total Cost
$402,186
Indirect Cost
$71,516
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
Roxby, Alison C; Fredricks, David N; Odem-Davis, Katherine et al. (2016) Changes in Vaginal Microbiota and Immune Mediators in HIV-1-Seronegative Kenyan Women Initiating Depot Medroxyprogesterone Acetate. J Acquir Immune Defic Syndr 71:359-66
Pintye, Jillian; Drake, Alison L; Kinuthia, John et al. (2016) A risk assessment tool for identifying pregnant and postpartum women who may benefit from pre-exposure prophylaxis (PrEP). Clin Infect Dis :
Masese, Linnet; Baeten, Jared M; Richardson, Barbra A et al. (2015) Changes in the contribution of genital tract infections to HIV acquisition among Kenyan high-risk women from 1993 to 2012. AIDS 29:1077-85
McClelland, R Scott; Richardson, Barbra A; Cherutich, Peter et al. (2015) A 15-year study of the impact of community antiretroviral therapy coverage on HIV incidence in Kenyan female sex workers. AIDS 29:2279-86
Odem-Davis, K; Fleming, T R (2015) A simulation study evaluating bio-creep risk in serial non-inferiority clinical trials for preservation of effect. Stat Biopharm Res 7:12-24
Kinuthia, John; Drake, Alison L; Matemo, Daniel et al. (2015) HIV acquisition during pregnancy and postpartum is associated with genital infections and partnership characteristics. AIDS 29:2025-33
Unger, Jennifer A; Matemo, Daniel; Pintye, Jillian et al. (2015) Patient-Delivered Partner Treatment for Chlamydia, Gonorrhea, and Trichomonas Infection Among Pregnant and Postpartum Women in Kenya. Sex Transm Dis 42:637-42
Strauss-Albee, Dara M; Fukuyama, Julia; Liang, Emily C et al. (2015) Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility. Sci Transl Med 7:297ra115
Lehman, Dara A; Ronen, Keshet; Blish, Catherine A et al. (2014) Systemic cytokine levels show limited correlation with risk of HIV-1 acquisition. J Acquir Immune Defic Syndr 66:135-9
Drake, Alison L; Wagner, Anjuli; Richardson, Barbra et al. (2014) Incident HIV during pregnancy and postpartum and risk of mother-to-child HIV transmission: a systematic review and meta-analysis. PLoS Med 11:e1001608

Showing the most recent 10 out of 20 publications