The Administrative Core is the operational center behind the entire P01 program. The Core will facilitate the research goals of the program by: * providing the organizational and administrative structure that insures maximally efficient use of resources among all investigators, * providing a centralized location for the tracking of expenditures and compilation of budgets, * insuring optimal dissemination of information among all investigators, * overseeing usage of the Tissue Repository Core to insure efficient distribution of human, macaque and rat tissues to all investigators, * directing usage of the Tissue Repository Core so that minimal numbers of animals are utilized, * funding new pilot projects in promising areas of research that complement the existing P01 projects while also opening additional avenues of research collaboration or expertise, arranging and coordinating the annual scientific retreat for the P01 program investigators, * assisting with the preparation and submission of manuscripts reporting P01 program scientific advances and also providing for page charges to support publication of these manuscripts * interacting with NICHD and the Office of Sponsored Projects Administration at the University of Kentucky to ensure compliance with all federal regulations * insuring that each scientific project maintains regulatory compliance by coordinating and accounting for all aspects of personnel training, protocol submission, approval, revision, and continuing review, (IACUC, recombinant DNA, biohazardous materials)

Public Health Relevance

The Administrative core is responsible for carefully and closely monitoring the entire operation of the P01 program, which is a multi-institutional program with 6 investigators at 3 different Universities. This core is the command central that deals with the day to day problems as well as insures that the long term research goals of the program are achieved.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Research Program Projects (P01)
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Special Emphasis Panel (ZHD1-DRG-D (41))
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University of Kentucky
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Cacioppo, Joseph A; Lin, Po-Ching Patrick; Hannon, Patrick R et al. (2017) Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture. Sci Rep 7:817
Puttabyatappa, Muraly; Al-Alem, Linah F; Zakerkish, Farnosh et al. (2017) Induction of Tissue Factor Pathway Inhibitor 2 by hCG Regulates Periovulatory Gene Expression and Plasmin Activity. Endocrinology 158:109-120
Choi, Yohan; Wilson, Kalin; Hannon, Patrick R et al. (2017) Coordinated Regulation Among Progesterone, Prostaglandins, and EGF-Like Factors in Human Ovulatory Follicles. J Clin Endocrinol Metab 102:1971-1982
Kim, Soon Ok; Trau, Heidi A; Duffy, Diane M (2017) Vascular endothelial growth factors C and D may promote angiogenesis in the primate ovulatory follicle. Biol Reprod 96:389-400
Cacioppo, Joseph A; Koo, Yongbum; Lin, Po-Ching Patrick et al. (2016) Generation of an estrogen receptor beta-iCre knock-in mouse. Genesis 54:38-52
Cerny, Katheryn L; Ribeiro, Rosanne A C; Jeoung, Myoungkun et al. (2016) Estrogen Receptor Alpha (ESR1)-Dependent Regulation of the Mouse Oviductal Transcriptome. PLoS One 11:e0147685
Oakley, Oliver R; Kim, Kee Jun; Lin, Po-Ching et al. (2016) Estradiol Synthesis in Gut-Associated Lymphoid Tissue: Leukocyte Regulation by a Sexually Monomorphic System. Endocrinology 157:4579-4587
Trau, Heidi A; Brännström, Mats; Curry Jr, Thomas E et al. (2016) Prostaglandin E2 and vascular endothelial growth factor A mediate angiogenesis of human ovarian follicular endothelial cells. Hum Reprod 31:436-44
Wilson, Kalin; Park, Jiyeon; Curry Jr, Thomas E et al. (2016) Core Binding Factor-? Knockdown Alters Ovarian Gene Expression and Function in the Mouse. Mol Endocrinol 30:733-47
Kim, Soon Ok; Duffy, Diane M (2016) Mapping PTGERs to the Ovulatory Follicle: Regional Responses to the Ovulatory PGE2 Signal. Biol Reprod 95:33

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