We propose a centralized, comprehensive database of mouse genetic and biological information together with software tools for analyzing, displaying and distributing mouse mapping information. The Program Project has four Research Projects: -a project to develop graphical tools for displaying mapping information and to develop database communication tools for integrating information from different databases, -a project to develop a collection of statistical, linkage analysis, and map construction tools for use by the mouse genetics community, -a project to obtain support from the Chromosome Committees and large mapping laboratories in maintaining and using the Mouse Genome Informatics databases and software tools, -a project to integrate comparative mapping information for other mammalian species and for testing database management systems. The Project also has six Core Projects: -a project to develop and maintain a relational database of raw mouse mapping information, -a project to develop and maintain a database of gene and mutation descriptions together with text search tools, -a project to develop and maintain a database of inbred strain characteristics, -a project to maintain existing databases such as GBASE until the Mouse Genome Database is ready, -a project to provide technical support for users, -a project to provide administrative support.
| Huntley, Rachael P; Sitnikov, Dmitry; Orlic-Milacic, Marija et al. (2016) Guidelines for the functional annotation of microRNAs using the Gene Ontology. RNA 22:667-76 |
| Bult, Carol J; Eppig, Janan T; Blake, Judith A et al. (2016) Mouse genome database 2016. Nucleic Acids Res 44:D840-7 |
| Bello, Susan M; Smith, Cynthia L; Eppig, Janan T (2015) Allele, phenotype and disease data at Mouse Genome Informatics: improving access and analysis. Mamm Genome 26:285-94 |
| Eppig, Janan T; Richardson, Joel E; Kadin, James A et al. (2015) Mouse Genome Database: From sequence to phenotypes and disease models. Genesis 53:458-73 |
| Zhu, Y; Richardson, J E; Hale, P et al. (2015) A unified gene catalog for the laboratory mouse reference genome. Mamm Genome 26:295-304 |
| Richardson, Joel E; Bult, Carol J (2015) Visual annotation display (VLAD): a tool for finding functional themes in lists of genes. Mamm Genome 26:567-73 |
| Li, You; Klena, Nikolai T; Gabriel, George C et al. (2015) Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature 521:520-4 |
| Eppig, Janan T; Blake, Judith A; Bult, Carol J et al. (2015) The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease. Nucleic Acids Res 43:D726-36 |
| Dolan, Mary E; Baldarelli, Richard M; Bello, Susan M et al. (2015) Orthology for comparative genomics in the mouse genome database. Mamm Genome 26:305-13 |
| Eppig, Janan T; Richardson, Joel E; Kadin, James A et al. (2015) Mouse Genome Informatics (MGI): reflecting on 25 years. Mamm Genome 26:272-84 |
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