The Administrative Core will be the central office for the administration of the Program Project. It will be coordinated through the Department of Pathology. The Principal Investigator, Dr. Darrel Stafford and the Administrator, Cynthia Taylor will meet regularly to go over items of interest pertaining to fiscal matters of all projects. The internal advisors will be contacted on a regular basis to keep members up to date on the research accomplishments. The external advisors will be invited to visit as needed to meet with the principal investigators of each sub project for comments and critique of research progress. These advisors will be charged with altering the scientific direction of each sub project should the need arise. The Administrative Core will insure smooth integration between the individual projects and will oversee weekly meetings of the investigators in room 442 of Wilson Hall. The Administrative Core will also coordinate the visits of the External Advisory committee and will be responsible for organizing the scientific program to be presented to the Advisory Committees. The Administrative Core will also organize all meetings of the Principal Investigators of the sub projects and will be responsible for the preparation of manuscripts, abstracts, human and animal rights protocols, monthly financial reports, and annual progress reports relating to the program project. Travel to scientific meetings by the members of the program project will be organized by the Administrative Core although travel requests will be in each individual sub project. The accounting mechanism for this program project will be carried through the Administrative Core as overseen by Ms. Cynthia Taylor, Administrator and with the direction of Dr. Darrel Stafford. All expenditures will be monitored by Ms. Taylor. The Administrative Core will also be responsible for communications with the NHLBI of the NIH, and the Office of Sponsored Research of the University of NC at Chapel Hill.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL006350-51
Application #
8375953
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
51
Fiscal Year
2012
Total Cost
$112,629
Indirect Cost
$36,528
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Bode, Michael F; Mackman, Nigel (2016) A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice. Thromb Res 146:46-50
Boulaftali, Yacine; Owens 3rd, A Phillip; Beale, Ashley et al. (2016) CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice. Arterioscler Thromb Vasc Biol 36:792-9
Owens 3rd, A Phillip; Edwards, Todd L; Antoniak, Silvio et al. (2015) Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol 35:2032-2041
Wu, Sangwook; Lee, Chang Jun; Pedersen, Lee G (2014) Analysis on long-range residue-residue communication using molecular dynamics. Proteins 82:2896-2901
Bode, Michael; Mackman, Nigel (2014) Regulation of tissue factor gene expression in monocytes and endothelial cells: Thromboxane A2 as a new player. Vascul Pharmacol 62:57-62
Wu, Sangwook; Beard, William A; Pedersen, Lee G et al. (2014) Structural comparison of DNA polymerase architecture suggests a nucleotide gateway to the polymerase active site. Chem Rev 114:2759-74
Perera, Lalith; Beard, William A; Pedersen, Lee G et al. (2014) Applications of quantum mechanical/molecular mechanical methods to the chemical insertion step of DNA and RNA polymerization. Adv Protein Chem Struct Biol 97:83-113
Parker, Christine H; Morgan, Christopher R; Rand, Kasper D et al. (2014) A conformational investigation of propeptide binding to the integral membrane protein ?-glutamyl carboxylase using nanodisc hydrogen exchange mass spectrometry. Biochemistry 53:1511-20
Boulaftali, Yacine; Hess, Paul R; Getz, Todd M et al. (2013) Platelet ITAM signaling is critical for vascular integrity in inflammation. J Clin Invest 123:908-16
Mutoh, Shingo; Sobhany, Mack; Moore, Rick et al. (2013) Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling. Sci Signal 6:ra31

Showing the most recent 10 out of 57 publications