This core provides the following services essential to the success of the overall program: Personnel recruitment, promotions, hiring, terminations and payroll Scheduling/Tracking of training and certifications of personnel to ensure compliance with local and federal guidelines for: Occupational Health, Hazardous Waste, Radiation Safety, Fire Safety, Blood Borne Pathogens, HIPAA, and IACUC Coordination of financial information: Including budgeting, projections of expenditures, purchase of equipment, auditing oversight of purchases made on credit cards and compliance with Federal standards on expenditures Travel arrangements and reimbursement Preparation of non-competing renewals and manuscripts Entering/Verifying the entry of PPG publications into Pubmed Central Responsible for tracking of all laboratory equipment and for annual audits of equipment and space Coordinate research conferences and audiovisual equipment Computer support, website support and LAN Administration Interface with Health Science Center Central Services and Administration Maintenance and repair of laboratory equipment Design and fabrication of new equipment for projects and cores Maintenance Program for the hypo-and hyperbaric chambers Assistance preparing and updating IACUC animal protocols

Public Health Relevance

The Administration Core provides services essential to the success of the overall program, including human resources, fiscal matters, and regulatory compliance.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Heart, Lung, and Blood Initial Review Group (HLBP)
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University of Colorado Denver
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Keller, Amy C; Knaub, Leslie A; Miller, Matthew W et al. (2015) Saxagliptin restores vascular mitochondrial exercise response in the Goto-Kakizaki rat. J Cardiovasc Pharmacol 65:137-47
Ostriker, Allison; Horita, Henrick N; Poczobutt, Joanna et al. (2014) Vascular smooth muscle cell-derived transforming growth factor-? promotes maturation of activated, neointima lesion-like macrophages. Arterioscler Thromb Vasc Biol 34:877-86
Geary, Kate; Knaub, Leslie A; Schauer, Irene E et al. (2014) Targeting mitochondria to restore failed adaptation to exercise in diabetes. Biochem Soc Trans 42:231-8
Stearman, Robert S; Cornelius, Amber R; Lu, Xiao et al. (2014) Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension. Am J Respir Crit Care Med 189:1110-20
El Kasmi, Karim C; Pugliese, Steven C; Riddle, Suzette R et al. (2014) Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension. J Immunol 193:597-609
Lehman, Allison M B; Montford, John R; Horita, Henrick et al. (2014) Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells. Mol Pharmacol 86:570-9
Wang, Daren; Zhang, Hui; Li, Min et al. (2014) MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts. Circ Res 114:67-78
Horita, Henrick; Furgeson, Seth B; Ostriker, Allison et al. (2013) Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension. J Am Heart Assoc 2:e000188
Gupta, Vivek; Gupta, Nilesh; Shaik, Imam H et al. (2013) Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension. J Control Release 167:189-99
Reusch, Jane E B; Bridenstine, Mark; Regensteiner, Judith G (2013) Type 2 diabetes mellitus and exercise impairment. Rev Endocr Metab Disord 14:77-86

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