Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL018646-35
Application #
8459917
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
35
Fiscal Year
2013
Total Cost
$225,414
Indirect Cost
$38,242
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Zwang, N A; Zhang, R; Germana, S et al. (2016) Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant 16:2624-38
Newton, Ryan; Priyadharshini, Bhavana; Turka, Laurence A (2016) Immunometabolism of regulatory T cells. Nat Immunol 17:618-25
Madariaga, M L L; Spencer, P J; Michel, S G et al. (2016) Effects of Lung Cotransplantation on Cardiac Allograft Tolerance Across a Full Major Histocompatibility Complex Barrier in Miniature Swine. Am J Transplant 16:979-86
Wang, Zhaohui; Pratts, Shannon G; Zhang, Huiping et al. (2016) Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Mol Oncol 10:553-65
Hotta, Kiyohiko; Aoyama, Akihiro; Oura, Tetsu et al. (2016) Induced regulatory T cells in allograft tolerance via transient mixed chimerism. JCI Insight 1:
Sihag, Smita; Haas, Michael S; Kim, Karen M et al. (2016) Natural IgM Blockade Limits Infarct Expansion and Left Ventricular Dysfunction in a Swine Myocardial Infarct Model. Circ Cardiovasc Interv 9:e002547
Madariaga, M L; Michel, S G; La Muraglia 2nd, G M et al. (2015) Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma. Am J Transplant 15:1580-90
Huynh, Alexandria; DuPage, Michel; Priyadharshini, Bhavana et al. (2015) Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability. Nat Immunol 16:188-96
Priyadharshini, Bhavana; Turka, Laurence A (2015) T-cell energy metabolism as a controller of cell fate in transplantation. Curr Opin Organ Transplant 20:21-8
Aoyama, A; Tonsho, M; Ng, C Y et al. (2015) Long-term lung transplantation in nonhuman primates. Am J Transplant 15:1415-20

Showing the most recent 10 out of 272 publications