The function of this core is to provide administrative coordination and statistical support of the entire program, including: arranging meetings, handling budgets and procurements, assisting with preparation of manuscripts and progress reports, and maintaining liaison between the numerous groups interacting in this Program. Dr. Madsen will have primary responsibility for coordinating the program, along with Dr. Cosimi, who will oversee interactions among the individual projects. In these positions, Drs Madsen and Cosimi play active and important roles and will be assisted by Ms. Karla Stenger, who will have daily administrative responsibility for the program. Dr. Shoenfeld will review all statistical tools and analyses in the Program.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
Project #
Application #
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Massachusetts General Hospital
United States
Zip Code
Tonsho, Makoto; Michel, Sebastian; Ahmed, Zain et al. (2014) Heart transplantation: challenges facing the field. Cold Spring Harb Perspect Med 4:
Haspot, F; Li, H W; Lucas, C L et al. (2014) Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells. Am J Transplant 14:49-58
Kawai, Tatsuo; Sachs, David H; Sykes, Megan et al. (2013) HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 368:1850-2
Madariaga, M L; Michel, S G; Tasaki, M et al. (2013) Induction of cardiac allograft tolerance across a full MHC barrier in miniature swine by donor kidney cotransplantation. Am J Transplant 13:2558-66
Yamada, Y; Boskovic, S; Aoyama, A et al. (2012) Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant 12:330-40
Nadazdin, Ognjenka; Boskovic, Svjetlan; Wee, Siew-Lin et al. (2011) Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates. J Immunol 187:4589-97
Alessandrini, Alessandro; De Haseth, Stephanie; Fray, Michael et al. (2011) Dendritic cell maturation occurs through the inhibition of GSK-3?. Cell Immunol 270:114-25
Nadazdin, Ognjenka; Abrahamian, Gregory; Boskovic, Svjetlan et al. (2011) Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. J Surg Res 168:294-300
Nadazdin, Ognjenka; Boskovic, Svjetlan; Murakami, Toru et al. (2011) Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med 3:86ra51
Veillette, Gregory R; Sahara, Hisashi; Meltzer, Andrew J et al. (2011) Autoimmune sensitization to cardiac myosin leads to acute rejection of cardiac allografts in miniature swine. Transplantation 91:1187-91

Showing the most recent 10 out of 236 publications