Core A has been a critical element in this Program Project since .its inception. There are two components to this core. The CHS portion of Core A provides human native and modified lipoproteins (and lipoprotein deficient serum) and leukocytes, human and mouse endothelial cells, and general services to the Projects and other Cores. The MRL portion of Core A provides analytical chemistry assays for the Projects and other Cores. This core is a cost-effective way of providing these essential services to the component Projects and other cores.

Public Health Relevance

This core constitutes a cost-effective means of providing lipoproteins and cells as well as routine assays'to. the component Projects and other cores in this Program Project, which is. dedicated to understanding lipid and lipoprotein metabolism in atherosclerosis.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL030568-30
Application #
8446361
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
30
Fiscal Year
2013
Total Cost
$273,411
Indirect Cost
$95,871
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Yan, Xinmin; Lee, Sangderk; Gugiu, B Gabriel et al. (2014) Fatty acid epoxyisoprostane E2 stimulates an oxidative stress response in endothelial cells. Biochem Biophys Res Commun 444:69-74
Joo, Jong Wha J; Sul, Jae Hoon; Han, Buhm et al. (2014) Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies. Genome Biol 15:r61
Mangul, Serghei; Caciula, Adrian; Al Seesi, Sahar et al. (2014) Transcriptome assembly and quantification from Ion Torrent RNA-Seq data. BMC Genomics 15 Suppl 5:S7
Albright, Jody; Quizon, Pamela M; Lusis, Aldons J et al. (2014) Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery. BMC Med Genomics 7:51
Hormozdiari, Farhad; Kostem, Emrah; Kang, Eun Yong et al. (2014) Identifying causal variants at loci with multiple signals of association. Genetics 198:497-508
L├╝scher, Thomas F; Landmesser, Ulf; von Eckardstein, Arnold et al. (2014) High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target. Circ Res 114:171-82
Jumabay, Medet; Abdmaulen, Raushan; Ly, Albert et al. (2014) Pluripotent stem cells derived from mouse and human white mature adipocytes. Stem Cells Transl Med 3:161-71
Ghazalpour, Anatole; Bennett, Brian J; Shih, Diana et al. (2014) Genetic regulation of mouse liver metabolite levels. Mol Syst Biol 10:730
Han, Buhm; Kang, Eun Yong; Raychaudhuri, Soumya et al. (2014) Fast pairwise IBD association testing in genome-wide association studies. Bioinformatics 30:206-13
Hasin-Brumshtein, Yehudit; Hormozdiari, Farhad; Martin, Lisa et al. (2014) Allele-specific expression and eQTL analysis in mouse adipose tissue. BMC Genomics 15:471

Showing the most recent 10 out of 638 publications