Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL033009-17
Application #
6593847
Study Section
Project Start
2002-05-01
Project End
2003-04-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
17
Fiscal Year
2002
Total Cost
$274,326
Indirect Cost
Name
Harvard University
Department
Type
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Lange, Janina R; Metzner, Claus; Richter, Sebastian et al. (2017) Unbiased High-Precision Cell Mechanical Measurements with Microconstrictions. Biophys J 112:1472-1480
Zhang, Guangzhi; Chen, Xian; Ohgi, Junji et al. (2016) Biomechanical simulation of thorax deformation using finite element approach. Biomed Eng Online 15:18
Lange, Janina R; Steinwachs, Julian; Kolb, Thorsten et al. (2015) Microconstriction arrays for high-throughput quantitative measurements of cell mechanical properties. Biophys J 109:26-34
Lang, Nadine R; Skodzek, Kai; Hurst, Sebastian et al. (2015) Biphasic response of cell invasion to matrix stiffness in three-dimensional biopolymer networks. Acta Biomater 13:61-7
An, Steven S; Askovich, Peter S; Zarembinski, Thomas I et al. (2011) A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening. Respir Res 12:8
Marinkovic, Marina; Diez-Silva, Monica; Pantic, Ivan et al. (2009) Febrile temperature leads to significant stiffening of Plasmodium falciparum parasitized erythrocytes. Am J Physiol Cell Physiol 296:C59-64
An, Steven S; Kim, Jina; Ahn, Kwangmi et al. (2009) Cell stiffness, contractile stress and the role of extracellular matrix. Biochem Biophys Res Commun 382:697-703
Shore, Stephanie A; Williams, Erin S; Zhu, Ming (2008) No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. J Appl Physiol 105:1127-33
Leung, Lester Y; Tian, David; Brangwynne, Clifford P et al. (2007) A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels. FASEB J 21:2064-73
Lenormand, Guillaume; Bursac, Predrag; Butler, James P et al. (2007) Out-of-equilibrium dynamics in the cytoskeleton of the living cell. Phys Rev E Stat Nonlin Soft Matter Phys 76:041901

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