The Computer, Electronics and Statistics Core will function as a general resource available to all of the projects. The consolidation of expertise in the areas of computer hardware and software, electronics, data acquisition, optics, image and signal processing, and statistics will enable the Core to provide support and services to the various projects in a highly coordinated and efficient manner. The Core provides technical expertise and leads software/hardware development efforts supporting the research conducted in the projects. Technical support includes: i) providing information to all investigators about the use of hardware and software in operation in their respective laboratories, ii) performing the system administration of the computers and the network, and iii) assisting in the development of small applications required for simple data analysis. Software developed in this core is related to i) simulation of cardiac excitation in the heart, and ii) processing of optical and electrical signals from the heart. System development includes design and integration of software/hardware systems for data and image acquisition. Statistical support: In collaboration with the Center for Outcomes Research the Core offers methodological expertise and collaborates in the design, implementation, understanding and analysis of basic and clinical research.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL039707-19
Application #
7921516
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2009-09-01
Project End
2011-08-31
Budget Start
2009-09-01
Budget End
2010-08-31
Support Year
19
Fiscal Year
2009
Total Cost
$341,411
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Pedrón-Torrecilla, Jorge; Rodrigo, Miguel; Climent, Andreu M et al. (2016) Noninvasive Estimation of Epicardial Dominant High-Frequency Regions During Atrial Fibrillation. J Cardiovasc Electrophysiol 27:435-42
Filgueiras-Rama, David; Jalife, José (2016) STRUCTURAL AND FUNCTIONAL BASES OF CARDIAC FIBRILLATION. DIFFERENCES AND SIMILARITIES BETWEEN ATRIA AND VENTRICLES. JACC Clin Electrophysiol 2:1-3
Herron, Todd J; Rocha, Andre Monteiro Da; Campbell, Katherine F et al. (2016) Extracellular Matrix-Mediated Maturation of Human Pluripotent Stem Cell-Derived Cardiac Monolayer Structure and Electrophysiological Function. Circ Arrhythm Electrophysiol 9:e003638
Guillem, María S; Climent, Andreu M; Rodrigo, Miguel et al. (2016) Presence and stability of rotors in atrial fibrillation: evidence and therapeutic implications. Cardiovasc Res 109:480-92
Takemoto, Yoshio; Ramirez, Rafael J; Yokokawa, Miki et al. (2016) Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes. JACC Basic Transl Sci 1:143-154
Willis, B Cicero; Pandit, Sandeep V; Ponce-Balbuena, Daniela et al. (2016) Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation 133:2348-59
Abriel, Hugues; Rougier, Jean-Sébastien; Jalife, José (2015) Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death. Circ Res 116:1971-88
Atienza, Felipe; Climent, Andreu M; Guillem, María S et al. (2015) Frontiers in Non-invasive Cardiac Mapping: Rotors in Atrial Fibrillation-Body Surface Frequency-Phase Mapping. Card Electrophysiol Clin 7:59-69
Rabinovitch, A; Biton, Y; Braunstein, D et al. (2015) Singular Value Decomposition of Optically-Mapped Cardiac Rotors and Fibrillatory Activity. J Phys D Appl Phys 48:
Atienza, Felipe; Climent, Andreu M; Guillem, María S et al. (2015) Frontiers in noninvasive cardiac mapping rotors in atrial fibrillation-body surface frequency-phase mapping. Card Electrophysiol Clin 7:59-69

Showing the most recent 10 out of 251 publications