Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL047049-19
Application #
8213816
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2011-02-01
Project End
2013-01-31
Budget Start
2011-02-01
Budget End
2012-01-31
Support Year
19
Fiscal Year
2011
Total Cost
$341,270
Indirect Cost
Name
Boston University
Department
Type
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Cushing, Leah; Costinean, Stefan; Xu, Wei et al. (2015) Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature. PLoS Genet 11:e1005238
Mori, Munemasa; Mahoney, John E; Stupnikov, Maria R et al. (2015) Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development 142:258-67
Cushing, Leah; Jiang, Zhihua; Kuang, Pingping et al. (2015) The roles of microRNAs and protein components of the microRNA pathway in lung development and diseases. Am J Respir Cell Mol Biol 52:397-408
Tagne, Jean-Bosco; Mohtar, Omar R; Campbell, Joshua D et al. (2015) Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb. Respir Res 16:22
Jiang, Zhihua; Cushing, Leah; Ai, Xingbin et al. (2014) miR-326 is downstream of Sonic hedgehog signaling and regulates the expression of Gli2 and smoothened. Am J Respir Cell Mol Biol 51:273-83
Guha, Arjun; Vasconcelos, Michelle; Zhao, Rui et al. (2014) Analysis of Notch signaling-dependent gene expression in developing airways reveals diversity of Clara cells. PLoS One 9:e88848
Mahoney, John E; Mori, Munemasa; Szymaniak, Aleksander D et al. (2014) The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors. Dev Cell 30:137-50
Jean, Jyh-Chang; George, Elizabeth; Kaestner, Klaus H et al. (2013) Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation. PLoS One 8:e54806
Tagne, Jean-Bosco; Gupta, Sumeet; Gower, Adam C et al. (2012) Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors. PLoS One 7:e29907
Jiang, Zhihua; Yu, Nan; Kuang, Pingping et al. (2012) Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm. J Biol Chem 287:5979-87

Showing the most recent 10 out of 92 publications