This Core provides computer, electronics, and instrumentation support services to Program Project Grant Investigators. The services are an essential part of the Projects'protocol design, animal maintenance, data acquisition and data analyses of Projects 1-4. Specific services range from creating/repairing instrumentation for acute and chronic animal experimentation to managing a World Wide Web server, to precision machining of custom mechanical parts. The personnel in this core are responsible for developing and implementing state of the art microcomputer technology and software, and for developing new instrumentation to meet the research needs of the Program Project. Instrumentation and computer technologies developed by the various investigators are made available to all members of the Program Project team. This core also provides Imaging support for immunohistochemical, densitometric, morphometric, and stereological analyses. In addition Core B will continue to support the development and use of mathematical modeling as a quantitative way to test new and integrative physiological concepts. Core investigators bring multiple skills to Core B. Robert Hester is a cardiovascular physiologist and a computer, instrumentation, and'microscopy expert with a graduate degree in biomedical engineering. Thomas Coleman is a cardiovascular physiologist and systems analyst who has a graduate degree in electrical engineering. Thomas Adair is a cardiovascular physiologist with expertise in the area of morphometric, stereological techniques, and quantitative image analysis. Heather Drummond is a cardiovascular physiologist and expert in confocal microscopy and image analysis. Brent Shows is the network administrator (Novell and Microsoft network certified) with extensive experience in computer network management and maintenance as well as repair of electronic equipment.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL051971-19
Application #
8374564
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2011-12-01
Budget End
2012-11-30
Support Year
19
Fiscal Year
2012
Total Cost
$286,378
Indirect Cost
$92,896
Name
University of Mississippi Medical Center
Department
Type
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216
Yang, Hui; Sun, Wanqing; Quan, Nanhu et al. (2016) Cardioprotective actions of Notch1 against myocardial infarction via LKB1-dependent AMPK signaling pathway. Biochem Pharmacol 108:47-57
Taylor, Erin B; Ryan, Michael J (2016) Understanding mechanisms of hypertension in systemic lupus erythematosus. Ther Adv Cardiovasc Dis :
Dasinger, John Henry; Intapad, Suttira; Backstrom, Miles A et al. (2016) Intrauterine growth restriction programs an accelerated age-related increase in cardiovascular risk in male offspring. Am J Physiol Renal Physiol 311:F312-9
DeLeon-Pennell, Kristine Y; Tian, Yuan; Zhang, Bai et al. (2016) CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling. Circ Cardiovasc Genet 9:14-25
Tostes, Rita C; Carneiro, Fernando S; Carvalho, Maria Helena C et al. (2016) Reactive oxygen species: players in the cardiovascular effects of testosterone. Am J Physiol Regul Integr Comp Physiol 310:R1-14
Ma, Yonggang; Yabluchanskiy, Andriy; Iyer, Rugmani Padmanabhan et al. (2016) Temporal neutrophil polarization following myocardial infarction. Cardiovasc Res 110:51-61
Lindsey, Merry L; Iyer, Rugmani Padmanabhan; Jung, Mira et al. (2016) Matrix metalloproteinases as input and output signals for post-myocardial infarction remodeling. J Mol Cell Cardiol 91:134-40
Hall, John E (2016) Renal Dysfunction, Rather Than Nonrenal Vascular Dysfunction, Mediates Salt-Induced Hypertension. Circulation 133:894-906
Harvey, Taylor W; Engel, Jason E; Chade, Alejandro R (2016) Vascular Endothelial Growth Factor and Podocyte Protection in Chronic Hypoxia: Effects of Endothelin-A Receptor Antagonism. Am J Nephrol 43:74-84
Blenck, Christa L; Harvey, Pamela A; Reckelhoff, Jane F et al. (2016) The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circ Res 118:1294-312

Showing the most recent 10 out of 662 publications