This Core provides computer, electronics, and instrumentation support services to Program Project Grant Investigators. The services are an essential part of the Projects'protocol design, animal maintenance, data acquisition and data analyses of Projects 1-4. Specific services range from creating/repairing instrumentation for acute and chronic animal experimentation to managing a World Wide Web server, to precision machining of custom mechanical parts. The personnel in this core are responsible for developing and implementing state of the art microcomputer technology and software, and for developing new instrumentation to meet the research needs of the Program Project. Instrumentation and computer technologies developed by the various investigators are made available to all members of the Program Project team. This core also provides Imaging support for immunohistochemical, densitometric, morphometric, and stereological analyses. In addition Core B will continue to support the development and use of mathematical modeling as a quantitative way to test new and integrative physiological concepts. Core investigators bring multiple skills to Core B. Robert Hester is a cardiovascular physiologist and a computer, instrumentation, and'microscopy expert with a graduate degree in biomedical engineering. Thomas Coleman is a cardiovascular physiologist and systems analyst who has a graduate degree in electrical engineering. Thomas Adair is a cardiovascular physiologist with expertise in the area of morphometric, stereological techniques, and quantitative image analysis. Heather Drummond is a cardiovascular physiologist and expert in confocal microscopy and image analysis. Brent Shows is the network administrator (Novell and Microsoft network certified) with extensive experience in computer network management and maintenance as well as repair of electronic equipment.
| Shekhar, Shashank; Cunningham, Mark W; Pabbidi, Mallikarjuna R et al. (2018) Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches. Eur J Pharmacol 833:531-544 |
| Quan, Nanhu; Wang, Lin; Chen, Xu et al. (2018) Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1? pathway. J Mol Cell Cardiol 115:170-178 |
| Lindsey, Merry L; Mouton, Alan J; Ma, Yonggang (2018) Adding Reg3? to the acute coronary syndrome prognostic marker list. Int J Cardiol 258:24-25 |
| Brooks, Heddwen L; Lindsey, Merry L (2018) Guidelines for authors and reviewers on antibody use in physiology studies. Am J Physiol Heart Circ Physiol 314:H724-H732 |
| Aberdein, Nicola; Dambrino, Robert J; do Carmo, Jussara M et al. (2018) Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance. Am J Physiol Regul Integr Comp Physiol 314:R478-R488 |
| Eddy, Adrian C; Bidwell 3rd, Gene L; George, Eric M (2018) Pro-angiogenic therapeutics for preeclampsia. Biol Sex Differ 9:36 |
| do Carmo, Jussara M; da Silva, Alexandre A; Moak, Sydney P et al. (2018) Role of melanocortin 4 receptor in hypertension induced by chronic intermittent hypoxia. Acta Physiol (Oxf) :e13222 |
| Lindsey, Merry L; Bolli, Roberto; Canty Jr, John M et al. (2018) Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol 314:H812-H838 |
| Chen, Xu; Li, Xuan; Zhang, Wenyan et al. (2018) Activation of AMPK inhibits inflammatory response during hypoxia and reoxygenation through modulating JNK-mediated NF-?B pathway. Metabolism 83:256-270 |
| Ma, Yonggang; Mouton, Alan J; Lindsey, Merry L (2018) Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction. Transl Res 191:15-28 |
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