The functions of Core Unit A are as follows: 1) To provide all the administrative and fiscal services that are required for support of the research activities of the Projects and the Core Units; 2) To coordinate all the clinical regulatory activities of all the components of the Program Project; 3) To interact with US Federal, Greek, EU and local regulatory agencies, as required; 4) To organize all the communications between components of the Program Project; 5) To coordinate and support the activities of the Internal and External Advisory committees 6) To organize and coordinate the scholarly activities of the Program Project including biweekly teleconference-lab meetings of the Seattle-New York-Thessaloniki investigators, 7) To organize the bimonthly evaluation and planning meetings of the executive committee of the Program Project. 8) To coordinate the fulfillment by all components of the Program Project of administrative requirements concerning biosafety, animal welfare etc 9) To assist the Principal Investigator in preparation of reports to NIH, the NHLBI DSMB and other agencies, as required.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL053750-16
Application #
7799414
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2009-09-01
Project End
2014-08-31
Budget Start
2009-09-01
Budget End
2011-03-31
Support Year
16
Fiscal Year
2010
Total Cost
$206,341
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Constantinou, Varnavas C; Bouinta, Asimina; Karponi, Garyfalia et al. (2017) Poor stem cell harvest may not always be related to poor mobilization: lessons gained from a mobilization study in patients with ?-thalassemia major. Transfusion 57:1031-1039
Gori, Jennifer L; Butler, Jason M; Kunar, Balvir et al. (2017) Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates. Stem Cells Transl Med 6:864-876
Psatha, Nikoletta; Karponi, Garyfalia; Yannaki, Evangelia (2016) Optimizing autologous cell grafts to improve stem cell gene therapy. Exp Hematol 44:528-39
Li, Li B; Ma, Chao; Awong, Geneve et al. (2016) Silent IL2RG Gene Editing in Human Pluripotent Stem Cells. Mol Ther 24:582-91
Karponi, Garyfalia; Psatha, Nikoletta; Lederer, Carsten Werner et al. (2015) Plerixafor+G-CSF-mobilized CD34+ cells represent an optimal graft source for thalassemia gene therapy. Blood 126:616-9
Vierstra, Jeff; Reik, Andreas; Chang, Kai-Hsin et al. (2015) Functional footprinting of regulatory DNA. Nat Methods 12:927-30
Liu, Mingdong; Maurano, Matthew T; Wang, Hao et al. (2015) Genomic discovery of potent chromatin insulators for human gene therapy. Nat Biotechnol 33:198-203
Qi, Heyuan; Liu, Mingdong; Emery, David W et al. (2015) Functional validation of a constitutive autonomous silencer element. PLoS One 10:e0124588
Polak, Paz; Karli?, Rosa; Koren, Amnon et al. (2015) Cell-of-origin chromatin organization shapes the mutational landscape of cancer. Nature 518:360-364
Watts, Korashon L; Beard, Brian C; Wood, Brent L et al. (2014) No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model. Exp Hematol 42:497-504

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