The purpose of the Clinical Core is to provide critical support for individual projects, including (1) assistance with recruitment and screening of normal subjects, (2) the identification of patients with specific autonomic disorders, (3) nursing and paramedical support for the performance of individual studies, and (4) the management of clinical resources (equipment and space) in a cost-effective manner. Shared study rooms and equipment permit flexibility and will maximize the availability of computer data acquisition systems, and specialized equipment. The Clinical Core supports state-of-the-art techniques for the functional assessment of autonomic function in man. The Core has implemented new methods and techniques relevant to the study of cardiovascular regulation, and continues to develop novel approaches to the analysis of complex biomedical signals, which can be now applied to support individual projects.
The purpose of the Clinical Core (Core B) is to provide shared resources, equipment, techniques and support personnel to all investigators in this Program Project Grant. This is more cost-effective than having each project develop their own methodologies, and assures greater quality control.
|Kawai, Vivian K; Chung, Cecilia P; Solus, Joseph F et al. (2015) The ability of the 2013 American College of Cardiology/American Heart Association cardiovascular risk score to identify rheumatoid arthritis patients with high coronary artery calcification scores. Arthritis Rheumatol 67:381-5|
|Bestawros, Michael; Darbar, Dawood; Arain, Amir et al. (2015) Ictal asystole and ictal syncope: insights into clinical management. Circ Arrhythm Electrophysiol 8:159-64|
|Adefurin, A; Ghimire, L V; Kohli, U et al. (2015) Genetic variation in the ?1A-adrenergic receptor and phenylephrine-mediated venoconstriction. Pharmacogenomics J 15:310-5|
|Mar, Philip L; Raj, Vidya; Black, Bonnie K et al. (2014) Acute hemodynamic effects of a selective serotonin reuptake inhibitor in postural tachycardia syndrome: a randomized, crossover trial. J Psychopharmacol 28:155-61|
|Mai, Tu H; Wu, Jing; Diedrich, André et al. (2014) Calcitonin gene-related peptide (CGRP) in autonomic cardiovascular regulation and vascular structure. J Am Soc Hypertens 8:286-96|
|Gamboa, Alfredo; Okamoto, Luis E; Arnold, Amy C et al. (2014) Autonomic blockade improves insulin sensitivity in obese subjects. Hypertension 64:867-74|
|Ramirez, Claudia E; Okamoto, Luis E; Arnold, Amy C et al. (2014) Efficacy of atomoxetine versus midodrine for the treatment of orthostatic hypotension in autonomic failure. Hypertension 64:1235-40|
|Jeff, Janina M; Donahue, Brian S; Brown-Gentry, Kristin et al. (2014) Genetic variation in the *1-adrenergic receptor is associated with the risk of atrial fibrillation after cardiac surgery. Am Heart J 167:101-108.e1|
|Biaggioni, Italo (2014) New developments in the management of neurogenic orthostatic hypotension. Curr Cardiol Rep 16:542|
|Raj, Satish R (2014) Highlights in clinical autonomic neurosciences: Insights into the roles of the carotid body and carotid baroreceptor. Auton Neurosci 183:80-2|
Showing the most recent 10 out of 223 publications