Core B: Genetics Core The Genetics Core continues to build on the highly-successful service functions provided to PPG researchers in the previous grant. With highly-trained personnel and specialized instrumentation, this Core provides our researchers with transgenic mouse production, knock-out mouse production, high quality DMA sequencing and microsatellite genotyping. These facilities were well-known among national Core labs for their outstanding technical competence and cost-effectiveness. The transgenic animal lab, under the management of Dr. Thomas Saunders, has accumulated 18 years of experience producing transgenic mice, and 15 years experience in genetic knock-out methodology. The DMA sequencing lab has been in operation for 14 years, the last 12 of which were under the direction of Dr. Lyons. That laboratory has an outstanding reputation for reliability and cost-effectiveness. They recently acquired an Illumina BeadStation 500GX, and have begun providing high-throughput SNP typing services. All four of the PPG projects depend heavily on the Genetics Core. The services described here will be provided on a recharge basis, with members of this Program Project receiving preferential discounts.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL057346-14
Application #
8377024
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
14
Fiscal Year
2012
Total Cost
$133,339
Indirect Cost
$57,625
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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