Core C: Administrative Core The Administrative Core will provide support for the Program Director in coordinating the overall Program Project Grant. The specific responsibilities of the Administrative Core include: 1) overseeing the distribution of scientific core resources to the four individual research projects;2) managing the weekly PPG Seminar Series including scheduling, arranging for travel and itineraries for visiting outside speakers;3) developing and maintaining a website for the PPG to permit outside investigators access to services and reagents developed through the PPG;4) preparing annual budget reports as required by the University of Michigan and the National Institutes of Health;5) organizing the Program review by the External Adviosry Board and the Internal Adviosry Board;6) overall post-award management including fiscal oversight and assurance of compliance with NIH guidelines.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
Project #
Application #
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Michigan Ann Arbor
Ann Arbor
United States
Zip Code
Cao, Stewart Siyan; Kaufman, Randal J (2014) Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease. Antioxid Redox Signal 21:396-413
Adams, Elizabeth J; Chen, Xiao-Wei; O'Shea, K Sue et al. (2014) Mammalian COPII coat component SEC24C is required for embryonic development in mice. J Biol Chem 289:20858-70
Everett, Lesley A; Cleuren, Audrey C A; Khoriaty, Rami N et al. (2014) Murine coagulation factor VIII is synthesized in endothelial cells. Blood 123:3697-705
Ferris, Sean P; Kodali, Vamsi K; Kaufman, Randal J (2014) Glycoprotein folding and quality-control mechanisms in protein-folding diseases. Dis Model Mech 7:331-41
Han, Jaeseok; Kaufman, Randal J (2014) Measurement of the unfolded protein response to investigate its role in adipogenesis and obesity. Methods Enzymol 538:135-50
Groenendyk, Jody; Peng, Zhenling; Dudek, Elzbieta et al. (2014) Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis. Sci Signal 7:ra54
Wang, Shiyu; Kaufman, Randal J (2014) How does protein misfolding in the endoplasmic reticulum affect lipid metabolism in the liver? Curr Opin Lipidol 25:125-32
Ji, Y; Fish, P M; Strawn, T L et al. (2014) C-reactive protein induces expression of tissue factor and plasminogen activator inhibitor-1 and promotes fibrin accumulation in vein grafts. J Thromb Haemost 12:1667-77
Cao, Stewart S; Wang, Miao; Harrington, Jane C et al. (2014) Phosphorylation of eIF2? is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice. Inflamm Bowel Dis 20:712-22
Khoriaty, Rami; Vasievich, Matthew P; Jones, Morgan et al. (2014) Absence of a red blood cell phenotype in mice with hematopoietic deficiency of SEC23B. Mol Cell Biol 34:3721-34

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