This Core will continue to integrate the functions of a number of skilled personnel already present at the Children's Hospital and University of Cincinnati College of Medicine. Core B will provide pathology/histology collaboration for each investigator to determine any gross, microscopic and ultrastructural abnormalities of the mouse models and changes in gene expression. Murine cardiovascular physiology, both noninvasive and invasive will also be provided. All of the Projects will use this core. The two Co-Directors, Dr. Melissa Colbert and Dr. John Lorenz, are expert in the fields of murine cardiac histology/embryology and murine physiology, respectively. Both have been involved in a number of important collaborations over the years with PPG personnel (see Introduction to the overall Program Project Grant). Dr. Colbert will lead the histology/embryology facets of the Core while Dr. Lorenz will direct the physiology component.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL069779-10
Application #
8374764
Study Section
Special Emphasis Panel (ZHL1-PPG-D)
Project Start
Project End
2013-08-31
Budget Start
2012-01-01
Budget End
2012-12-31
Support Year
10
Fiscal Year
2012
Total Cost
$387,271
Indirect Cost
$89,583
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
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