The primary purpose of the Biochemical and Molecular Biology Core (Core C) is to centralize support for techniques that are common to a majority of the individual projects with this Program Project Grant application. This core is thus an important resource for the investigators of this application, the individuals in their laboratories and is an essential part of this Program Project. This core will provide project investigators with technical support, teaching, upkeep of particular key pieces of equipment and centralize supply sources for commonly-used molecular and biochemical techniques. We have also developed a repository of methods/protocols kept electronically through the PPG website, protocols that are available to all participants in the program. We will continue to develop additional techniques for measurement of reactive oxygen species (ROS), use of HPLC, etc.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
Project #
Application #
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Michigan State University
East Lansing
United States
Zip Code
Jackson, W F (2017) Potassium Channels in Regulation of Vascular Smooth Muscle Contraction and Growth. Adv Pharmacol 78:89-144
Jackson, William F; Boerman, Erika M (2017) Regional heterogeneity in the mechanisms of myogenic tone in hamster arterioles. Am J Physiol Heart Circ Physiol 313:H667-H675
Fink, Gregory D; Phelps, Jeremiah T (2017) Can we predict the blood pressure response to renal denervation? Auton Neurosci 204:112-118
Fink, Gregory D (2017) Does Tail-Cuff Plethysmography Provide a Reliable Estimate of Central Blood Pressure in Mice? J Am Heart Assoc 6:
Ayala-Lopez, Nadia; Thompson, Janice M; Watts, Stephanie W (2017) Perivascular Adipose Tissue's Impact on Norepinephrine-Induced Contraction of Mesenteric Resistance Arteries. Front Physiol 8:37
Ismail, Alex; Ayala-Lopez, Nadia; Ahmad, Maleeha et al. (2017) 3T3-L1 cells and perivascular adipocytes are not equivalent in amine transporter expression. FEBS Lett 591:137-144
Tykocki, Nathan R; Boerman, Erika M; Jackson, William F (2017) Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles. Compr Physiol 7:485-581
Thelen, Kyan; Ayala-Lopez, Nadia; Watts, Stephanie W et al. (2017) Expansion and Adipogenesis Induction of Adipocyte Progenitors from Perivascular Adipose Tissue Isolated by Magnetic Activated Cell Sorting. J Vis Exp :
Ayala-Lopez, Nadia; Watts, Stephanie W (2017) New actions of an old friend: perivascular adipose tissue's adrenergic mechanisms. Br J Pharmacol 174:3454-3465
Diaz-Otero, Janice M; Fisher, Courtney; Downs, Kelsey et al. (2017) Endothelial Mineralocorticoid Receptor Mediates Parenchymal Arteriole and Posterior Cerebral Artery Remodeling During Angiotensin II-Induced Hypertension. Hypertension 70:1113-1121

Showing the most recent 10 out of 97 publications