The primary purposes of the Imaging and Cell Biology Core are to provide central facilities and technical assistance for: 1.) imaging of live and fixed cells and tissues, and 2.) isolation of fresh nerve and vascular cells for physiological study (patch clamp, calcium imaging, ROS measurements, contraction assays) and 3.) culture and manipulation of nerve and other cells. By centralizing these core techniques, Core D will enable cost efficiency because a portion of technical help and laboratory facilities/equipment will be provided, avoiding a duplication of efforts and expenditure of money by the investigators. In addition, by providing technical help, Core D provides primary investigators with a degree of quality-control and consistency in experiments as well as additional time in which investigators can follow scientific pursuits.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL070687-10
Application #
8452158
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
2015-01-31
Budget Start
2013-02-01
Budget End
2014-01-31
Support Year
10
Fiscal Year
2013
Total Cost
$147,852
Indirect Cost
$50,554
Name
Michigan State University
Department
Type
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
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Kandlikar, Sachin S; Fink, Gregory D (2011) Splanchnic sympathetic nerves in the development of mild DOCA-salt hypertension. Am J Physiol Heart Circ Physiol 301:H1965-73
Jackson, William F (2011) Quick change artist: endothelium-derived relaxing factor in resistance arteries. Hypertension 57:686-8

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