The PI, Robin Felder, Ph.D., with the assistance of the Administrator, Beth McGrath, will provide routine management of the Program Project Grant from this core. The fact that Beth will be also working on Project 1 as a seasoned Research Assistant will provide unique continuity between the laboratory and administrative office. The core will oversee the finances of the project. It will allocate resources and finances to the individual subprojects and cores. It will provide a monthly financial review for project and core leaders. It will undertake the documentation and processing that is required for tracking of the expenditures and changes in personnel. The core will process purchase orders and service contracts for the project leaders. It will provide expert editorial assistance for preparation of manuscripts for all the principal investigators. It will convene the internal and external scientific review groups. It will handle the travel arrangements for the external review committee members and the remuneration for their expenses. It will schedule investigators'meetings and seminars and arrange for visiting professors and their itineraries. The Administrative Core will be responsible for the preparation of reports and summaries that are required by the NIH for administrative review. It will have a full time staff person to conduct statistical analyses for the data generated in the projects, and the final data sets will be kept on a secure web site to allow all PPG participants to view and comment on the ongoing productivity.

Public Health Relevance

The Administrative core is the central coordinating site for all the projects to assure there is an adherance to our core specific aims, and to facilitate communication, documentation and publication.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL074940-08
Application #
8374523
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2012-01-01
Budget End
2012-12-31
Support Year
8
Fiscal Year
2012
Total Cost
$437,639
Indirect Cost
$88,843
Name
University of Virginia
Department
Type
DUNS #
065391526
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Ye, Zhengmeng; Lu, Xi; Deng, Yi et al. (2018) In Utero Exposure to Fine Particulate Matter Causes Hypertension Due to Impaired Renal Dopamine D1 Receptor in Offspring. Cell Physiol Biochem 46:148-159
Yang, Yang; Chen, Caiyu; Fu, Chunjiang et al. (2018) Angiotensin II type 2 receptor inhibits expression and function of insulin receptor in rat renal proximal tubule cells. J Am Soc Hypertens 12:135-145
Li, Fengmin; Yang, Jian; Villar, Van Anthony M et al. (2018) Loss of renal SNX5 results in impaired IDE activity and insulin resistance in mice. Diabetologia 61:727-737
Wang, Xiaoyan; Villar, Van Anthony; Tiu, Andrew et al. (2018) Dopamine D2 receptor upregulates leptin and IL-6 in adipocytes. J Lipid Res 59:607-614
Luo, Hao; Chen, Caiyu; Guo, Li et al. (2018) Exposure to Maternal Diabetes Mellitus Causes Renal Dopamine D1 Receptor Dysfunction and Hypertension in Adult Rat Offspring. Hypertension 72:962-970
Wu, Gengze; Jose, Pedro A; Zeng, Chunyu (2018) Noncoding RNAs in the Regulatory Network of Hypertension. Hypertension 72:1047-1059
Asico, Laureano D; Cuevas, Santiago; Ma, Xiaobo et al. (2018) Nephron segment-specific gene expression using AAV vectors. Biochem Biophys Res Commun 497:19-24
Muntner, Paul; Whelton, Paul K; Woodward, Mark et al. (2018) A Comparison of the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline and the 2017 American Diabetes Association Diabetes and Hypertension Position Statement for U.S. Adults With Diabetes. Diabetes Care 41:2322-2329
Tiu, Andrew C; Bishop, Michael D; Asico, Laureano D et al. (2017) Primary Pediatric Hypertension: Current Understanding and Emerging Concepts. Curr Hypertens Rep 19:70
Diao, Zhenyu; Asico, Laureano D; Villar, Van Anthony M et al. (2017) Increased renal oxidative stress in salt-sensitive human GRK4?486V transgenic mice. Free Radic Biol Med 106:80-90

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