The aims of the Administrative Core are to provide: 1) administrative support for the Program Project Grant, conformity to guidelines/policies, requisite reporting, biostatistical support, and human resource management;and 2) budget oversight and centralization of shared budgetary items. The Core will provide assistance to the director in the handling of correspondence, forms, competitive and non-competitive renewals and acts as a liaison with the institution, the NIH/NHLBI and other entities. The Core will provide essential secretarial/clerical services to all investigators with regards to the preparation of manuscripts, reviews, articles, letters, travel arrangements, and arrangements for visiting scientists. The Core will make arrangements for regular research meetings of the program scientists and assist in organizing program seminars. It coordinates the advisory committees and provides orientation for Core users. All financial matters for the Program Project Grant are handled by the core, including the monitoring and status of service contracts, coordinating repair and service schedules. The Core will provide statistical analysis, experimental design and data quality assurance.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Heart, Lung, and Blood Initial Review Group (HLBP)
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Henry Ford Health System
United States
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Gordish, Kevin L; Beierwaltes, William H (2014) Resveratrol induces acute endothelium-dependent renal vasodilation mediated through nitric oxide and reactive oxygen species scavenging. Am J Physiol Renal Physiol 306:F542-50
Ortiz-Capisano, M Cecilia; Reddy, Mahendranath; Mendez, Mariela et al. (2013) Juxtaglomerular cell CaSR stimulation decreases renin release via activation of the PLC/IP(3) pathway and the ryanodine receptor. Am J Physiol Renal Physiol 304:F248-56
Atchison, Douglas K; Beierwaltes, William H (2013) The influence of extracellular and intracellular calcium on the secretion of renin. Pflugers Arch 465:59-69
Ortiz-Capisano, M Cecilia; Atchison, Douglas K; Harding, Pamela et al. (2013) Adenosine inhibits renin release from juxtaglomerular cells via an A1 receptor-TRPC-mediated pathway. Am J Physiol Renal Physiol 305:F1209-19
Ramseyer, Vanesa D; Garvin, Jeffrey L (2013) Tumor necrosis factor-ýý: regulation of renal function and blood pressure. Am J Physiol Renal Physiol 304:F1231-42
Beierwaltes, William H (2013) Endothelial dysfunction in the outer medullary vasa recta as a key to contrast media-induced nephropathy. Am J Physiol Renal Physiol 304:F31-2
Atchison, Douglas K; Harding, Pamela; Beierwaltes, William H (2013) Vitamin D increases plasma renin activity independently of plasma Ca2+ via hypovolemia and *-adrenergic activity. Am J Physiol Renal Physiol 305:F1109-17
Cabral, Pablo D; Garvin, Jeffrey L (2013) Less potassium coming out, less sodium going in: phenotyping ROMK knockout rats. Hypertension 62:240-1
Ren, Yilin; D'Ambrosio, Martin A; Wang, Hong et al. (2012) Mechanisms of carbon monoxide attenuation of tubuloglomerular feedback. Hypertension 59:1139-44
Beierwaltes, William H (2012) Are microRNAs the key to transforming renin progenitor cells in the afferent renal circulation? Am J Physiol Renal Physiol 302:F27-8

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